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Fig. 3 | BMC Cancer

Fig. 3

From: LncRNA WWC2-AS1 functions AS a novel competing endogenous RNA in the regulation of FGF2 expression by sponging miR-16 in radiation-induced intestinal fibrosis

Fig. 3

Knocking down WWC2-AS1 promotes proliferation, migration, invasion and fibrosis of colorectal cells in response to radiation. a Relative expression of WWC2-AS1 in CCD-18Co and NCM-460 cells with or without sh-WWC2-AS1 as indicated. b Cell viability was detected by MTT assay after WWC2-AS1 was knocked down in CCD-18Co and SEMFs cells. c Cell apoptosis was detected by FACS with AnnexinV. d Invasion and migration of cells were detected by Transwell assay and statistical results were shown in columns. e α-SMA and ColI in Cells treated as described in A were detected by Western Blot. Relative intensity was normalized to GAPDH and shown in columns. *P < 0.05, compared to control group

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BMC Cancer

ISSN: 1471-2407

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