Fig. 3
H2A.X Y142ph down-regulated the downstream factors of Ras pathway. The transcription of Ras-ERK1/2-targeted genes can be partially down-regulated by increased H2A.XY142ph. a The transcription of several genes was tested using real time PCR. b As detected using ChIP, reduced levels of H2A.XY142ph are present on the differentially expressed genes. Data presented as mean + SD, ns, no significant difference, * P < 0.05, ** P < 0.01, *** P < 0.001 (n = 3)