Effect of prior cancer on survival outcomes for patients with pancreatic adenocarcinoma: a propensity score analysis

He, Chaobin; Zhang, Yu; Cai, Zhiyuan; Lin, Xiaojun

doi:10.1186/s12885-019-5744-8

Table 1 Comparisons of clinicopathological characteristics of patients

From: Effect of prior cancer on survival outcomes for patients with pancreatic adenocarcinoma: a propensity score analysis

Characteristic		Before PSM				After PSM				Effect size
Characteristic		Without prior cancer	With prior cancer	Total number	P value	Without prior cancer	With prior cancer	Total number	P value	Effect size
Total number		8797	438	9235		4380	438	4818
Age (years)	≤ 60	2683	43	2726	< 0.001	429	43	472	1.000	0.001
Age (years)	> 60	6114	395	6509	< 0.001	3951	395	4346	1.000	0.001
Gender	Female	4201	213	4414	0.732	2138	213	2351	0.960	0.002
Gender	Male	4596	225	4821	0.732	2242	225	2467	0.960	0.002
Race	Black	1113	48	1161	0.186	519	48	567	0.487	0.020
	White	6937	361	7298		3512	361	3873
	Others	747	29	776		349	29	378
Tumor site	Head	5214	233	5447	0.018	2498	233	2731	0.051	0.241
	Body	1135	80	1215		574	80	654
	Tail	1143	60	1203		613	60	673
	Pancreatic duct	662	33	695		328	33	361
	Others	643	32	675		367	32	399
Tumor size (cm)	≤ 2	858	53	911	0.261	442	53	495	0.416	0.019
	2~4	4429	218	4647		2240	218	2458
	> 4	3510	167	3677		1698	167	1865
Tumor grade	Well	915	44	959	0.019	492	44	536	0.432	−0.020
	Moderate	3708	191	3899		1884	191	2075
	Poor	4024	187	4211		1896	187	2083
	Undifferentiated	150	16	166		108	16	124
T stage	T0	33	2	35	0.006	25	2	27	0.173	0.159
	TI	332	25	357		190	25	215
	TII	1848	118	1966		1013	118	1131
	TIII	4799	214	5013		2374	214	2588
	TIV	1785	79	1864		778	79	857
N stage	N0	4464	254	4718	0.012	2462	254	2716	0.735	−0.006
	N1	3398	146	3544		1502	146	1648
	N2	935	38	973		416	38	454
Metastasis	Absent	4728	243	4971	0.492	2402	243	2645	0.801	0.006
Metastasis	Present	4069	195	4264	0.492	1978	195	2173	0.801	0.006
TNM stage	I	551	48	559	0.001	358	48	406	0.237	0.172
	II	2623	131	2754		1345	131	1476
	III	1554	64	1618		699	64	763
	IV	4069	195	4264		1978	195	2173
Surgery	Performed	3408	161	3569	< 0.001	1610	161	1771	0.103	0.189
	Recommended, not performed	245	28	273		185	28	213
	Not recommended	5144	249	5393		2585	249	2834
Radiotherapy	No	7605	393	7998	0.052	3840	393	4233	0.220	−0.172
Radiotherapy	Yes	1192	45	1237	0.052	540	45	585	0.220	−0.172
Chemotherapy	No	3160	180	3340	0.029	1752	180	1932	0.683	0.005
Chemotherapy	Yes	5637	258	5895	0.029	2628	258	2886	0.683	0.005

LN Lymph node metastasis, TNM Tumor-node-metastasis stage

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ISSN: 1471-2407

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