Table 2 Genotypic distribution of SNPs in CCR5 promoter among control, CIN and CC groups
Control (N = 682) | CIN (n = 336) | CC (n = 488) | CIN vs CO | CC vs CO | CIN vs CC | ||
|---|---|---|---|---|---|---|---|
rs2227010 | GG | 28 (4.11%) | 11 (3.27%) | 24 (4.92%) | χ2 = 7.174, P* = 0.028 | χ2 = 0.522, P = 0.770 | χ2 = 6.099, P = 0.047 |
GA | 188 (27.56%) | 120 (35.72%) | 137 (28.07%) | ||||
AA | 466 (68.33%) | 205 (61.01%) | 327 (67.01%) | ||||
rs2734648 | GG | 143 (20.97%) | 109 (32.44%) | 131 (26.84%) | χ2 = 17.260, P = 1.78E-04 | χ2 = 5.623, P = 0.060 | χ2 = 3.658, P = 0.161 |
TG | 336 (49.26%) | 131 (38.99%) | 218 (44.67%) | ||||
TT | 203 (29.77%) | 96 (28.57%) | 139 (28.48%) | ||||
rs1799987 | AA | 121 (17.74%) | 93 (27.68%) | 110 (22.54%) | χ2 = 14.59, P = 6.78E-04 | χ2 = 4.249, P = 0.1195 | χ2 = 3.420, P = 0.181 |
GA | 315 (46.19%) | 126 (37.50%) | 208 (42.62%) | ||||
GG | 246 (36.07%) | 117 (34.82%) | 170 (34.84%) | ||||
rs1799988 | CC | 129 (18.91%) | 91 (27.08%) | 96 (19.67%) | χ2 = 9.808, P = 0.007 | χ2 = 0.231, P = 0.891 | χ2 = 6.636, P = 0.036 |
TC | 321 (47.07%) | 133 (39.59%) | 223 (45.70%) | ||||
TT | 232 (34.02%) | 112 (33.33%) | 169 (34.63%) | ||||
rs1800023 | AA | 147 (21.55%) | 105 (31.26%) | 127 (26.02%) | χ2 = 11.89, P = 0.003 | χ2 = 3.246, P = 0.1973 | χ2 = 2.904, P = 0.234 |
GA | 328 (48.10%) | 135 (40.17%) | 218 (44.67%) | ||||
GG | 207 (30.35%) | 96 (28.57%) | 143 (29.30%) | ||||
rs1800024 | TT | 43 (6.30%) | 24 (7.14%) | 26 (5.33%) | χ2 = 1.312, P = 0.519 | χ2 = 1.510, P = 0.470 | χ2 = 1.166, P = 0.558 |
CT | 234 (34.32%) | 125 (37.21%) | 183 (37.50%) | ||||
CC | 405 (59.38%) | 187 (55.65%) | 279 (57.17%) |