Table 1 Allelic distribution of SNPs in CCR5 promoter among control, CIN and CC groups
CO (N = 682) | CIN (n = 336) | CC (n = 488) | CIN vs CO | CC vs CO | CIN vs CC | |||||
|---|---|---|---|---|---|---|---|---|---|---|
P* | OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | |||||
rs2227010 | G | 244 (17.89%) | 142 (21.13%) | 185 (18.95%) | 0.079 | 1.230 (0.976–1.550) | 0.511 | 1.074 (0.869–1.327) | 0.276 | 0.873 (0.683–1.115) |
A | 1120 (82.11%) | 530 (78.87%) | 791 (81.05%) | |||||||
rs2734648 | G | 622 (45.60%) | 349 (51.93%) | 480 (49.18%) | 0.007 | 1.289 (1.071–1.551) | 0.087 | 1.154 (0.979–1.361) | 0.272 | 1.117 (0.917–1.359) |
T | 742 (54.40%) | 323 (48.07%) | 496 (50.82%) | |||||||
rs1799987 | A | 557 (40.84%) | 312 (46.43%) | 428 (43.85%) | 0.016 | 1.256 (1.042–1.513) | 0.145 | 1.132 (0.958–1.336) | 0.302 | 0.901 (0.740–1.098) |
G | 807 (59.16%) | 360 (53.57%) | 548 (56.15%) | |||||||
rs1799988 | C | 579 (42.44%) | 315 (46.88%) | 415 (42.52%) | 0.058 | 1.196 (0.994–1.440) | 0.972 | 1.003 (0.849–1.184) | 0.08 | 0.838 (0.688–1.022) |
T | 785 (57.55%) | 357 (53.12%) | 561 (57.48%) | |||||||
rs1800023 | A | 622 (45.60%) | 345 (51.34%) | 472 (48.36%) | 0.015 | 1.259 (1.046–1.514) | 0.187 | 1.117 (0.948–1.317) | 0.235 | 0.888 (0.729–1.080) |
G | 742 (54.40%) | 327 (48.66%) | 504 (51.64%) | |||||||
rs1800024 | T | 320 (23.46%) | 173 (25.74%) | 235 (24.08%) | 0.258 | 1.131 (0.914–1.400) | 0.729 | 1.035 (0.853–1.255) | 0.441 | 0.915 (0.729–1.148) |
C | 1044 (76.54%) | 499 (74.26%) | 741 (75.92%) | |||||||