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Table 1 Distribution of characteristics of two independent patient cohorts with RCC by FBXO11 expression

From: Prevalence and prognostic value of FBXO11 expression in patients with clear cell renal cell carcinoma

Patient characteristics

Training cohort (150 patients)

Total

P Value

Validation cohort (77patients)

Total

P Value

Low

High

Low

High

Gender

   

0.227

   

0.644

 Male

41

63

104

 

17

25

42

 

 Female

23

23

46

 

16

19

35

 

Age, years

   

0.048

   

0.099

 <57

38

37

75

 

19

17

36

 

 ≥57

26

49

75

 

14

27

41

 

Tumor size

   

0.738

   

0.394

 ≤4 cm

30

35

65

 

15

14

29

 

 4 cm–7 cm

24

35

59

 

13

24

37

 

 ≥7 cm

10

16

26

 

5

6

11

 

Fuhrman grade

   

0.003

   

0.111

 I-II

47

39

86

 

22

19

41

 

 III

14

37

51

 

8

16

24

 

 IV

3

10

13

 

3

9

12

 

Pathologic stage

   

0.065

   

0.291

 T1

58

66

124

 

28

29

57

 

 T2

5

13

18

 

2

8

10

 

 T3

1

7

8

 

2

5

7

 

 T4

0

0

0

 

1

2

3

 

Lymph node status

   

0.764

   

0.423

 No

62

84

146

 

31

39

70

 

 N1- Nx

2

5

4

 

2

5

7

 

Distant metastasis

   

0.131

   

0.894

 Absent

64

83

147

 

31

41

72

 

 Present

0

3

3

 

2

3

5

 

Sarcomatoid

   

0.846

   

0.894

 Absent

59

80

139

 

31

41

72

 

 Present

5

6

11

 

2

3

5

 

Type of surgery

   

0.395

   

0.836

 Radical nephrectomy

42

62

104

 

21

29

50

 

 Partial nephrectomy.

22

24

46

 

12

15

27

 

UISS score

   

0.021

   

0.012

 1

52

52

104

 

26

20

46

 

 2

11

29

40

 

7

23

30

 

 3

1

5

6

 

0

1

1

 

SSIGN score

   

0.205

   

0.070

 0–3

58

70

128

 

27

26

53

 

 4–7

6

14

20

 

3

13

16

 

 ≥8

3

5

8

 

3

5

8

 
  1. Bold values are considered statistically significant (p < 0.05)