Patient characteristics | Training cohort (150 patients) | Total | P Value | Validation cohort (77patients) | Total | P Value | ||
---|---|---|---|---|---|---|---|---|
Low | High | Low | High | |||||
Gender | Â | Â | Â | 0.227 | Â | Â | Â | 0.644 |
 Male | 41 | 63 | 104 |  | 17 | 25 | 42 |  |
 Female | 23 | 23 | 46 |  | 16 | 19 | 35 |  |
Age, years | Â | Â | Â | 0.048 | Â | Â | Â | 0.099 |
 <57 | 38 | 37 | 75 |  | 19 | 17 | 36 |  |
 ≥57 | 26 | 49 | 75 |  | 14 | 27 | 41 |  |
Tumor size | Â | Â | Â | 0.738 | Â | Â | Â | 0.394 |
 ≤4 cm | 30 | 35 | 65 |  | 15 | 14 | 29 |  |
 4 cm–7 cm | 24 | 35 | 59 |  | 13 | 24 | 37 |  |
 ≥7 cm | 10 | 16 | 26 |  | 5 | 6 | 11 |  |
Fuhrman grade | Â | Â | Â | 0.003 | Â | Â | Â | 0.111 |
 I-II | 47 | 39 | 86 |  | 22 | 19 | 41 |  |
 III | 14 | 37 | 51 |  | 8 | 16 | 24 |  |
 IV | 3 | 10 | 13 |  | 3 | 9 | 12 |  |
Pathologic stage | Â | Â | Â | 0.065 | Â | Â | Â | 0.291 |
 T1 | 58 | 66 | 124 |  | 28 | 29 | 57 |  |
 T2 | 5 | 13 | 18 |  | 2 | 8 | 10 |  |
 T3 | 1 | 7 | 8 |  | 2 | 5 | 7 |  |
 T4 | 0 | 0 | 0 |  | 1 | 2 | 3 |  |
Lymph node status | Â | Â | Â | 0.764 | Â | Â | Â | 0.423 |
 No | 62 | 84 | 146 |  | 31 | 39 | 70 |  |
 N1- Nx | 2 | 5 | 4 |  | 2 | 5 | 7 |  |
Distant metastasis | Â | Â | Â | 0.131 | Â | Â | Â | 0.894 |
 Absent | 64 | 83 | 147 |  | 31 | 41 | 72 |  |
 Present | 0 | 3 | 3 |  | 2 | 3 | 5 |  |
Sarcomatoid | Â | Â | Â | 0.846 | Â | Â | Â | 0.894 |
 Absent | 59 | 80 | 139 |  | 31 | 41 | 72 |  |
 Present | 5 | 6 | 11 |  | 2 | 3 | 5 |  |
Type of surgery | Â | Â | Â | 0.395 | Â | Â | Â | 0.836 |
 Radical nephrectomy | 42 | 62 | 104 |  | 21 | 29 | 50 |  |
 Partial nephrectomy. | 22 | 24 | 46 |  | 12 | 15 | 27 |  |
UISS score | Â | Â | Â | 0.021 | Â | Â | Â | 0.012 |
 1 | 52 | 52 | 104 |  | 26 | 20 | 46 |  |
 2 | 11 | 29 | 40 |  | 7 | 23 | 30 |  |
 3 | 1 | 5 | 6 |  | 0 | 1 | 1 |  |
SSIGN score | Â | Â | Â | 0.205 | Â | Â | Â | 0.070 |
 0–3 | 58 | 70 | 128 |  | 27 | 26 | 53 |  |
 4–7 | 6 | 14 | 20 |  | 3 | 13 | 16 |  |
 ≥8 | 3 | 5 | 8 |  | 3 | 5 | 8 |  |