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Table 1 Summary of CSH cases coexistent with DLBCL

From: Generalized crystal-storing histiocytosis with diffuse large B-cell lymphoma and monoclonal gammopathy in a Chinese elderly woman: a case report

Report/Year

Age/sex

Symptoms / History

Diagnosis

Ig type

Sites of CSH

Clinical course

Kaufmann/1996 [5]

61/F

Subcutaneous masses

G-CSH with LPL in transformation to a large cell lymphoma

IgM kappa

IgG lambda

Skin, LN

Not reported

Jones/1999 [4]

70/M

Splenomegaly

G-CSH with LPL

IgM kappa

BM, LN

Transformed to DLBCL at 24mos

Thorson/2000 [7]

77/F

Bilateral cervical lymphadenopathy

G-CSH with Low-grade monocytoid B-cell lymphoma

lambda

Parotid and submandibular glands, LN

Transformed to DLBCL at 8ys

Li JJ /2015 [6]

80/F

Bilateral periorbital swelling

L-CSH with WM

IgM kappa

Skin

Transformed to DLBCL at 6ys and died of disease

Kawano/2013 [8]

80/M

Asymptomatic/

Gastric DLBCL 13 years ago(CR)

L-CSH without LP-PCD

None

Lung

Live free of disease at a 23mos follow-up

Present case

74/F

Abdominal pain, fever, subcutaneous masses

G-CSH with DLBCL

IgM kappa

Soft tissue, LN

Live with disease at a 1y follow-up

  1. F: Female; M: Male; L-CSH: Localized crystal-storing histiocytosis; G-CSH: Generalized crystal-storing histiocytosis; DLBCL: Diffuse large B-cell lymphoma; LPL: Lymphoplasmacytic lymphoma; WM: Waldenström’s macroglobulinemia; LP-PCD: Lymphoproliferative or plasma cell disorder; CR: Complete remission; LN: Lymph node; BM: Bone marrow; mo: Month; y: Year