Fig. 5From: A survivin-responsive, conditionally replicating adenovirus induces potent cytocidal effects in adult T-cell leukemia/lymphomaRelationship between survivin promoter activity and the cytotoxic effects of Surv.m-CRA. We examined the relationship between the survivin promoter activity of CRAs in ATL cell lines and HTLV-1-infected T-cell lines and the IC50 of Surv.m-CRAs in the cell lines. The coefficient of determination, denoted as R2, is 0.99356. Oh13T, which exhibited complete resistance to Surv.m-CRA treatment, was excluded from this analysisBack to article page