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Table 1 Patient characteristics

From: Fluoropyrimidine with or without platinum as first-line chemotherapy in patients with advanced gastric cancer and severe peritoneal metastasis: a multicenter retrospective study

Characteristics

All patients

FP group

F group

p-value

(n = 129)

(n = 64)

(n = 65)

No. (%)

No. (%)

No. (%)

Age (years)

 Median (range)

65 (24–94)

62 (27–94)

67 (24–89)

0.02

 < 65

61 (47)

36 (56)

25 (38)

0.04

> 65

68 (53)

28 (44)

40 (62)

 

Sex

 Male

68 (53)

33 (52)

35 (54)

0.80

 Female

61 (47)

31 (48)

30 (46)

 

ECOG PS

 0

9 (7)

4 (6)

5 (8)

 

 1

68 (53)

41 (64)

27 (42)

 

 2

44 (34)

16 (25)

28 (43)

 

 3

7 (5)

2 (3)

5 (8)

 

 4

1 (1)

1 (2)

0 (0)

 

 0–1

77 (60)

45 (70)

32 (49)

0.01

 2–4

52 (40)

19 (30)

33 (51)

 

Histology

 Intestinal

22 (17)

10 (16)

12 (18)

0.81

 Diffuse

102 (79)

52 (81)

50 (77)

 

 Unknown

5 (4)

2 (3)

3 (5)

 

Disease status

 Advanced

120 (93)

58 (91)

62 (95)

0.29

 Recurrent

9 (7)

6 (9)

3 (5)

 

Primary tumor

 Presence

113 (88)

54 (84)

59 (91)

0.27

 Absence

16 (12)

10 (16)

6 (9)

 

Primary site

 Stomach

123 (95)

59 (92)

64 (98)

0.09

 GEJ

6 (5)

5 (8)

1 (2)

 

No. of metastatic sites

 1–2

100 (78)

49 (77)

51 (78)

0.80

> 3

29 (22)

15 (23)

14 (22)

 

Target lesion

 Presence

56 (43)

24 (38)

32 (49)

0.18

 Absence

73 (57)

40 (62)

33 (51)

 

Subtype of SPM

 Massive ascites

62 (48)

39 (61)

23 (35)

0.01

 Inadequate oral intake

35 (27)

16 (25)

19 (29)

 

 Both

32 (25)

9 (14)

23 (35)

 

Serum albumin level (g/ml)

 Median (range)

3.1 (1.8–4.4)

3.1 (1.8–4.3)

3.1 (1.8–4.4)

0.87

Serum CRP level (mg/dl)

 Median (range)

2.2 (0.0–24.0)

1.8 (0.1–20.7)

2.6 (0.0–24.0)

0.86

  1. CRP C-reactive protein, ECOG PS: Eastern Cooperative Oncology Group performance status, GEJ gastroesophageal junction, SPM severe peritoneal metastasis