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Table 4 Multivariate Cox regression analyses predicting overall survival and penis cancer-specific survival

From: Prognostic value of lymphovascular invasion in patients with squamous cell carcinoma of the penis following surgery

Variables

Overall survival

Penile carcinoma-specific survival

Hazard Ratio

95% CI

P

Hazard Ratio

95% CI

P

T stage

  

0.066

  

0.420

Tx + Ta + T1

1.000

Referent

1.000

Referent

T2

1.405

1.016–1.945

0.040

1.219

0.701–2.118

0.483

T3

1.528

1.046–2.230

0.028

1.302

0.709–2.391

0.395

T4

2.134

0.839–5.428

0.112

2.786

0.797–9.740

0.109

Lymph nodes status

  

< 0.001

  

< 0.001

Nx

1.000

Referent

1.000

Referent

N0

0.522

0.253–1.079

0.079

0.361

0.104–1.247

0.107

N1-N3

1.290

0.596–2.791

0.518

1.645

0.465–5.820

0.440

Grade

  

0.068

  

0.171

G1

1.000

Referent

1.000

Referent

G2

1.057

0.750–1.488

0.752

1.342

0.691–2.607

0.386

G3 + G4

1.484

1.002–2.197

0.049

1.913

0.924–3.959

0.080

Distant metastasis

1.796

1.042–3.095

0.035

2.938

1.484–5.815

0.002

regional lymph nodes removed

0.457

0.314–0.666

< 0.001

0.734

0.424–1.270

0.269

Surgery

1.768

1.063–2.940

0.028

1.992

0.947–4.192

0.069

LVI

1.403

1.017–1.936

0.039

1.324

0.798–2.198

0.277

  1. SCCP squamous cell carcinoma of the penis; LVI lymphovascular invasion; CI confidence intervals
  2. Significant values in bold