Predictors of distant metastasis in parotid acinic cell carcinoma

BMC Cancer

Table 2 Univariate and cox model analysis of the predictors for distant metastasis control survival

Variables	Univariate	Cox model
	Log rank test	HR (95% CI)	p
Age (< 55 vs ≥55)	0.258
Sex (Male vs female)	0.371
Tumor stage (T1 + T2 vs T3 + T4)	0.004	2.674(0.978–7.995)	0.089
Node stage (N0 vs N+)	0.011	3.612(0.287–13.611)	0.483
Disease stage (I + II vs III + IV)	< 0.001	3.874(1.843–9.664)	< 0.001
Resection extent (TP vs PP + SP)^a	0.482
Tumor site (Deep vs superficial)	0.337
Margin (Positive vs negative)	0.687
Perineural invasion	0.141
Lymphovascular invasion	0.009	2.813(0.846–9.473)	0.219
High grade transformation	0.028	4.219(1.948–15.553)	< 0.001
IPN metastasis^b	0.048	1.854(1.061–4.144)	0.011
Radiotherapy	0.035	0.644 (0.433–0.893)	0.005

^aTP total parotidectomy, PP partial parotidectomy, SP superficial parotidectomy; ^bIPN intraparotid node metastasis

ISSN: 1471-2407