Table 4 Predictive factors of 2-year recurrence rate
Variables | N | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | ||
Gender, male | 120 | 1.46 (0.19–10.99) | 0.713 | 1.44 (0.19–10.73) | 0.725 |
Age (years) | |||||
< 40(ref) | 14 | ||||
40–60 | 91 | 1.51 (0.65–3.82) | 0.633 | ||
> =60 | 25 | 2.70 (0.55–8.15) | 0.221 | ||
BMI (kg/m2), > = 24 | 61 | 1.71 (0.76–3.84) | 0.193 | ||
Cirrhotic state, Uncompensated | 32 | 1.09 (0.44–2.72) | 0.849 | ||
APRI | |||||
< 0.5(ref) | 32 | ||||
0.5–1.5 | 64 | 0.72 (0.22–2.39) | 0.590 | ||
> =1.5 | 34 | 1.19 (0.46–3.07) | 0.723 | ||
Pre-treatment ascites | 18 | 4.83 (0.65–35.77) | 0.124 | ||
Pre-treatment EGV | 7 | 1.22 (0.39–2.16) | 0.256 | ||
Tumor size (mm), > 20 | 64 | 1.13 (0.52–2.45) | 0.756 | ||
ALT (IU/L), > 40 | 47 | 1.29 (0.56–2.96) | 0.551 | ||
AST (IU/L), > 40 | 45 | 2.28 (0.86–6.05) | 0.098 | 2.25 (0.85–5.98) | 0.104 |
PT (sec), > 13 | 23 | 1.29 (0.38–4.38) | 0.683 | ||
ALP (IU/L), > 110 | 41 | 1.84 (0.73–4.63) | 0.194 | ||
TBA (μmol/L), > 10 | 48 | 1.11 (0.50–2.49) | 0.799 | ||
ALBI grade | |||||
1(ref) | 98 | ||||
2 | 32 | 1.04 (0.42–2.61) | 0.931 | ||
3 | 0 | ||||
PLT(10^9/L), < 100 | 53 | 1.03 (0.47–2.29) | 0.939 | ||
AFP (ng/ml), > 20 | 59 | 1.08 (0.50–2.35) | 0.849 | ||
Child-Pugh, B | 11 | 1.62 (0.62–4.69) | 0.214 | ||
Conventional RFA | 84 | 2.12 (1.16–4.62) | 0.027 | 2.11 (1.16–4.43) | 0.041 |