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Table 6 Comparison of genotype frequencies of the four polymorphisms according to gastric cancer recurrence after surgery

From: Genetic polymorphisms of vascular endothelial growth factor (VEGF) associated with gastric cancer recurrence after curative resection with adjuvant chemotherapy

VEGF SNP

 

Advanced Gastric Cancer after curative resection (N = 71)

Recurrence after resection (N = 28)

P-value (adjust)

OR (95% CI)

−936 C > T

   

0.06 (0.09)

 

Dominant CC vs CT + TT

CC

41

22

 

1.0

\

CT + TT

30

6

 

0.37 (0.13–1.03)

−634 C > G

   

0.75 (0.94)

 

Dominant GG vs CG + CC

GG

23

10

 

1.0

 

CG + GG

48

18

 

0.86 (0.34–2.16)

−2578 C > A

   

0.79 (0.97)

 

Dominant CC vs CA + AA

CC

41

17

 

1.0

 

CA + AA

30

11

 

0.88 (0.36–2.16)

−1612 G > A

   

0.46 (0.62)

 

Dominant GG vs GA + AA

GG

51

18

 

1.0

 

GA + AA

20

10

 

1.42 (0.56–3.59)

  1. NOTE: Adjusted for age, gender, smoking status, and alcohol ingestion
  2. CI confidence interval, OR odds ratio