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Table 1 Description of the vitronectin and nuclei morphometric measurements of control tissues and NB primary tumors

From: Vitronectin as a molecular player of the tumor microenvironment in neuroblastoma

Parameter

Median

Mean

SD

Range

Q3

Normal control tissues other than liver (nā€‰=ā€‰12)

IPP

Nuclei

Density

308.10

305

99.75

94.10ā€“477.70

355

%SA

7.30

7.90

3.35

4ā€“14

8.80

Inter. VN

%SA

1.57

3.92

5.70

0.42ā€“17

3.67

Terr. VN

%SA

0.04

0.07

0.07

0ā€“0.20

0.15

Densito

VN ratio of pixels

Weak

0.04

1

1.50

0ā€“4

1.75

Moderate

2.25

10.95

13

0.06ā€“35

22.90

Strong

1

2

2.60

0ā€“9

2.95

H-score

20.45

46.40

52.51

0.16ā€“163

82.50

Liver samples (nā€‰=ā€‰5)

IPP

Nuclei

Density

616

1846.70

2384.30

472ā€“6051.70

3767.80

%SA

4

3.80

2.05

2ā€“7

5.50

Inter. VN

%SA

20

19

11.40

3ā€“31

29.50

Terr. VN

%SA

3

2.50

1.30

0.65ā€“4

3.50

Densito

VN ratio of pixels

Weak

2.50

2.85

2.30

0.30ā€“6

5.15

Moderate

67

64.55

8.30

50ā€“71

69.50

Strong

12.75

13.50

2.70

10ā€“17

16

H-score

175.80

172.60

11.60

152.25ā€“181.35

179.55

Primary tumors (nā€‰=ā€‰91)

IPP

Nuclei

Density

560

1074.25

1455.80

95ā€“6793

739

%SA

11.75

11.70

6.30

0.35ā€“29.70

15.50

Inter. VN

%SA

9.35

12.25

10.95

0.02ā€“40.97

18.20

Terr. VN

%SA

0.71

2.95

4.45

0.01ā€“20.70

4.50

Densito

VN ratio of pixels

Weak

0.80

1.60

2.40

0.01ā€“14.65

2.10

Moderate

35

36.10

24.70

0.05ā€“88.10

56.75

Strong

3.55

12.85

17.85

0.01ā€“61.85

20.40

H-score

110.91

112.85

78.55

1.07ā€“257.60

183.80

  1. Descriptors of vitronectin (VN) immunoreactivity and nuclei according to their morphometric measurements are shown. IPP: Image Pro-Plus; Densito: DensitoQuant; Inter.VN: Interterritorial VN; Terr.VN: Territorial VN. Density: number of objects/mm2; %SA: percentage of stained area. SD: Standard deviation; Q3: third quartile