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Table 1 Clinicopathologic variables and the expression of CD8, FoxP3, PD-1, and PD-L1 in stage IVa-b NPC patients

From: PD-1 high expression predicts lower local disease control in stage IV M0 nasopharyngeal carcinoma

Variables   n PD-1 high p PD-L1 high p CD8 high p FoxP3 p
Total   60 34 56.7%   55 91.7%   36 60.0%   52 86.7%  
Gender male 47 26 55.3% 0.760 42 89.4% 0.575 28 59.6% 0.988 39 83.0% 0.150
female 13 8 61.5%   13,100%   8 61.5%   13,100%  
Age <medial 28 15 53.6% 0.795 25 89.3% 0.657 20 71.4% 0.208 26 92.9% 0.228
≥medial 32 19 59.4%   30 93.8%   16 50.0%   26 81.3%  
Pathology WHO I 3 2 66.7% 1.000 3100% 1.000 0 0% 0.337 3100% 0.566
WHO II 57 32 56.1%   55 91.7%   33 57.9%   49 85.9%  
T stage T1–2 4 1 25.0% 0.346 4100.0% 0.695 3 75.0% 0.314 3 75.0% 0.446
T3 12 8 66.7%   11 91.7%   6 50.0%   12,100%  
T4 44 25 56.8%   40 90.9%   27 61.4%   37 84.1%  
N stage N1 18 11 61.1% 0.310 16 88.9% 0.853 13 72.2% 0.317 16 88.9% 0.489
N2 25 16 64.0%   23 92.0%   15 60.0%   22 88.0%  
N3 17 7 41.2%   16 94.1%   8 47.1%   14 82.4%  
TNM stage IVa 43 27 62.8% 0.156 39 90.7% 1.000 28 65.1% 0.157 38 88.4% 0.779
IVb 17 7 41.2%   16 94.1%   8 47.1%   14 82.4%