Table 7 In silico Analysis of the SNP rs2385677 by Human Spicing Finder (v.3.1)
Method | Motif G/C Allele | Motif A/T Allele | Threshold Value | Result |
|---|---|---|---|---|
ESE Finder | ccgcctg (71.23) | – | – | SF2/ASF (IgM-BRCA1) site broken |
– | gacccgtc (78.30) | 75.05 | New SC35 binding Site | |
– | cccgtc (76.04) | 73.86 | New SRp55 binding site | |
EIEs (Zhang et al) | Acccgc | – | – | Site broken |
Cccgcc | ||||
Ccgcct | ||||
Cgcctg | ||||
Gcctgg | ||||
Cctggt | ||||
IEs from (Zhang et al) | – | gtctgg | – | New Site |
Other Splicing motifs - Exonic Splicing Regulatory Sequences (Goren et al) | Cgcctg Gcctgg | – | – | Site broken |