Fig. 5
From: Lineage relationship between prostate adenocarcinoma and small cell carcinoma
DNA microarray data analysis. a Expression difference between LNCaP* and LNCaP is visualized by the MA plot. b Based on array signal intensity values, B2M level is lower in LNCaP* compared with LNCaP, LNCaP/PENK and LNCaP/AGR2. Signal values in log2 are indicated on the y-axis. The second and third panels have a different set of values on the y-axis than the first panel. c The PCA plot of the four LNCaP datasets shows the difference in the transcriptomes of the four cell types. PLIER (probe logarithmic intensity error estimation) is a multi-array normalization method to produce improved signals by accounting for experimentally observed patterns in feature behavior, and handling error at low and high signal values. A dendrogram depiction of the data is also shown