Table 5 Univariate and multivariate Cox proportional hazards analyses of MMP19 expression and overall survival for patients with colorectal cancer in the validation cohort
From: High expression of MMP19 is associated with poor prognosis in patients with colorectal cancer
Factor | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Gender | 1.000(0.547–1.827) | 0.999 | ||
Age | 1.416(0.788–2.543) | 0.245 | ||
T category | 2.542(1.396–4.628) | 0.002 | 1.854(1.054–3.260) | 0.032 |
N stage | 1.975 (1.354–2.881) | < 0.001 | 1.856(1.226–2.810) | 0.003 |
Tumor location | 0.808(0.450–1.450) | 0.475 | ||
Histologic type | 1.206(0.374–3.893) | 0.754 | ||
Grade | 1.155(0.762-1.751) | 0.496 | ||
Intramural vascular invasion | 2.419(1.312–4.458) | 0.005 | 0.927(0.435–1.975) | 0.210 |
Perineural invasion | 1.412(0.680–2.932) | 0.355 | ||
MMP19 | 5.807(2.702–12.483) | < 0.001 | 5.595(2.573–12.164) | < 0.001 |