Skip to main content

Table 3 Association between MMP19 expression and clinicopathological factors in colorectal cancer

From: High expression of MMP19 is associated with poor prognosis in patients with colorectal cancer

Characteristics

Total

MMP19 expression

P value

Low expression

High expression

Gender

   

0.144

 Male

122

56(56.6)

66(66.7)

 

 Female

76

43(43.4)

33(33.3)

 

Age

   

0.190

  ≥ 60

121

65(65.7)

56(56.6)

 

 <60

77

34(34.3)

43(43.4)

 

Primary site

   

0.776

 colon

92

45(45.5)

47(47.5)

 

 rectum

106

54(54.5)

52(52.5)

 

Histologic type

   

0.756

 Adenocarcinoma

187

94(94.9)

93(93.9)

 

 Mucinous adenocarcinoma

11

5(5.1)

6(6.1)

 

Histologic grade

   

0.177

 Well

54

24(24.2)

30(30.3)

 

 Moderate

99

56(56.6)

43(43.4)

 

 Poor

45

19(19.2)

26(26.3)

 

T stage

   

0.052

 T2

17

10(10.1)

7(7.1)

 

 T3

72

43(43.4)

29(29.3)

 

 T4

109

46(46.5)

63(63.6)

 

Node status

   

0.029

 Negative

79

47(47.5)

32(32.3)

 

 Positive

119

52(52.5)

67(67.7)

 

Intramural vascular invasion

   

0.015

 Negative

156

85(85.9)

71(71.7)

 

 Positive

42

14(14.1)

28(28.3)

 

Perineural invasion

   

0.692

 Negative

168

85(85.9)

83(83.8)

 

 Positive

30

14(14.1)

16(16.2)

 

CEA status

   

0.045

 normal

137

75(75.8)

62(62.6)

 

 high

61

24(24.2)

37(37.4)

 
  1. Abbreviations: CEA carcinoembryonic antigen, MMP19 matrix metalloproteinase 19, T tumor, N node, M metastasis
  2. Bold type indicates statistical significance