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Table 1 Univariate and multivariate Cox proportional hazards analyses of MMP19 expression and overall survival for patients with colorectal cancer in the The Cancer Genome Atlas database

From: High expression of MMP19 is associated with poor prognosis in patients with colorectal cancer

Factor

Univariate analysis

Multivariate analysis

HR (95% CI)

P

HR (95% CI)

P

Gender

0.793(0.509–1.234)

0.303

 

NI

Age

1.029(1.010–1.084)

0.002

1.037(1.017–1.056)

< 0.001

T category

2.680(1.694–4.242)

< 0.001

2.045(1.260–3.320)

0.004

N stage

1.759(1.371–2.256)

< 0.001

1.573(1.199–2.064)

0.001

M stage

1.378(1.069–1.778)

0.013

1.092(0.829–1.440)

0.532

Tumor location

0.777(0.442–1.364)

0.379

  

MMP19

1.449(1.108–1.893)

0.007

1.401(1.036–1.894)

0.028

  1. Abbreviations: CI confidence interval, HR hazard ratio, MMP19 matrix metalloproteinase 19, T tumor, N node, M metastasis
  2. Bold type indicates statistical significance