Fig. 1
From: High expression of MMP19 is associated with poor prognosis in patients with colorectal cancer
X-tile analyses of 5-year overall survival (OS) were performed using data from The Cancer Genome Atlas to determine the optimal cut-off values for the matrix metalloproteinase 19 (MMP19) mRNA levels. The sample of colorectal cancer (CRC) patients was equally divided into training and validation cohorts. a X-tile plots of the training sets are shown in the left panels, with plots of matched validation cohort shown in the smaller inset. b Optimal cut-off values highlighted by the black circles in the left panels are shown in histograms of the entire cohort (middle panels); 167 patients in the MMP19 low expression group, while 192 were in the high expression group, and (c) Kaplan–Meier plots are displayed in the right panels, χ2 = 12.602,P < 0.001