Fig. 5
From: Major vault protein suppresses lung cancer cell proliferation by inhibiting STAT3 signaling pathway
MVP knockdown activates STAT3, JAK2, and ERK in the transfected LLC cells. a Representative western blot of the indicated proteins in the transfected LLC cells after serum starvation and stimulation. b Representative western blot of nuclear STAT3 in the transfected LLC cells. c, d Quantification of the western blot in A and B. (n = 3, * P < 0.05, ** P < 0.01). e Luciferase reporter assay of STAT3 transcriptional activity in the transfected LLC cells. f Representative western blot of the indicated proteins in the transfected LLC cells after serum starvation and stimulation. g Quantification of the western blot. (n = 3, * P < 0.05, ** P < 0.01)