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Table 1 Univariate analysis of AIFM3 expression and clinical pathology factors

From: Clinical implications of a novel prognostic factor AIFM3 in breast cancer patients

Factors

Number (%)

AIFM3 expression

χ2

P

Crude OR (95 CI)

High (%)

Low (%)

Age(years)

   

1.254

0.740a

 

 ≤ 40

26(17.2)

14(53.8)

12(46.2)

 

0.318b

0.583(0.203-1.680)

 41-50

52(34.4)

34(65.4)

18(34.6)

 

0.903b

0.944(0.376-2.375)

 51-60

40(26.5)

25(62.5)

15(37.5)

 

0.712b

0.833(0.317-2.190)

 ≥61

33(21.9)

22(66.7)

11(33.3)

  

Reference

Tumor size

   

6.135

0.013a

 

 ≥ 3 cm

87(57.6)

62(71.3)

25(28.7)

 

0.014b

2.330(1.186-4.577)

 < 3 cm

64(42.4)

33(51.6)

31(48.4)

  

Reference

LN Metastases

   

11.824

0.001a

 

 negative

86(57.0)

44(51.2)

42(48.8)

  

Reference

 positive

65(43.0)

51(78.5)

14(21.5)

 

0.001b

3.477(1.681-7.194)

ER

   

0.266

0.606a

 

 negative

58(38.4)

35(60.3)

23(39.7)

  

Reference

 positive

93(61.6)

60(64.5)

33(35.5)

 

0.606b

1.195(0.608-2.349)

PR

   

1.160

0.281a

 

 negative

59(39.1)

34(57.6)

25(42.4)

  

Reference

 positive

92(60.9)

61(66.3)

31(33.7)

 

0.282b

1.447(0.738-2.837)

Ki67

   

1.051

0.305a

 

 negative

62(41.1)

42(67.7)

20(32.3)

  

Reference

 positive

89(58.9)

53(59.6)

36(40.4)

 

0.306b

0.701(0.355-1.384)

Her2

   

2.645

0.104a

 

 negative

101(66.9)

59(58.4)

42(42.6)

  

Reference

 positive

50(33.1)

36(72.0)

14(28.0)

 

0.106b

1.831(0.879-3.811)

Histological grade

   

1.902

0.398a

 

 2

124(82.1)

81(65.3)

43(34.7)

  

Reference

 3

14(9.3)

7(50.0)

7(50.0)

 

0.264b

0.531(0.175-1.612)

 unrated

13(8.6)

7(53.8)

6(46.2)

 

0.415b

0.619(0.196-1.959)

Molecular typing

   

7.935

0.047a

 

  Luminal A

60(39.7)

41(68.3)

19(31.7)

 

0.011b

3.596(1.337-9.673)

  Luminal B

48(31.8)

32(66.7)

16(33.3)

 

0.021b

3.333(1.200-9.256)

 Her-2

19(12.6)

13(68.4)

6(31.6)

 

0.048b

3.611(1.012-12.888)

 TNBC

24(15.9)

9(37.5)

15(62.5)

  

Reference

TNM staging

   

17.197

<0.001a

 

 I

38(25.2)

14(36.8)

24(63.2)

  

Reference

 II

75(49.6)

50(50.0)

25(50.0)

 

0.003b

3.429(1.517-7.749)

 III

38(25.2)

31(81.6)

7(18.4)

 

<0.001b

7.592(2.651-21.743)

  1. P-value a came from Pearson chi-square tests or Fisher’s Exact Test
  2. P-value b came from logistic regression analyses