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Table 3 Clinicopathologic characteristics and prognostic factor for survival of 432 ESCC patients

From: Comparison of minimally invasive Ivor Lewis esophagectomy and left transthoracic esophagectomy in esophageal squamous cell carcinoma patients: a propensity score-matched analysis

Characteristic Total (n = 432) MIILE (n = 216) Sweet (n = 216)
No p value No p value No p value
  OS DFS OS DFS OS DFS
Gender
 Male 366 0.505 0.393 181 0.551 0.422 185 0.748 0.679
 Female 66    35    31   
Age(year)
  < 65 267 0.902 0.943 132 0.126 0.189 135 0.158 0.179
  ≥ 65 165    84    81   
BMI (kg/m2)
  ≤ 18.5 86    33    53   
 18.5~25 287 0.277* 0.169* 156 0.717* 0.528* 131 0.244* 0.165*
  ≥ 25 59 0.182* 0.082* 27 0.053* 0.024* 32 0.789* 0.696*
Tumor location
 Upper and middle junction 21    11    10   
 Middle third 199 0.898** 0.964** 99 0.524** 0.471** 100 0.761** 0.616**
 Lower third 212 0.766** 0.853** 106 0.350** 0.331** 106 0.617** 0.445**
Tumor length(cm)
 ≤ 3 139 < 0.001 < 0.001 78 0.013 0.003 61 0.005 0.016
 >3 293    138    155   
Depth of invasion (T)
 T1–2 150 < 0.001 < 0.001 74 < 0.001 < 0.001 76 0.201 0.481
 T3–4 282    142    140   
Lymph node metastasis (N)
 N0 222 < 0.001 < 0.001 107 < 0.001 < 0.001 115 < 0.001 < 0.001
 N1–3 210    109    101   
Pathology stage (TNM)
 I 103 0.050*** 0.053*** 50 0.004*** 0.002*** 53 0.091*** 0.876***
 II 140 < 0.001**** < 0.001**** 68 < 0.001**** < 0.001**** 72 < 0.001**** < 0.001****
 III 189 < 0.001***** < 0.001***** 98 < 0.001***** < 0.001***** 91 < 0.001***** < 0.001*****
Atrial fibrillation
 Yes 123 0.144 0.086 56 0.493 0.594 67 0.124 0.038
 No 309    160    149   
Pneumonia complication (including ARDS)
 Yes 203 < 0.001 < 0.001 88 0.008 0.010 115 < 0.001 < 0.001
 No 229    128    101   
Postoperative complication
 Yes 258 < 0.001 < 0.001 110 0.294 0.424 148 < 0.001 < 0.001
 No 174    106    68   
  1. *Compared with low BMI group (≤18.5), log-rank. **Compared with upper third group, log-rank. ***I compared with II, log-rank;****II compared with III, log-rank; *****I compared with III, log-rank
  2. MIILE minimally invasive Ivor Lewis esophagectomy
  3. OS overall survival
  4. DFS disease-free survival
  5. BMI body mass index
  6. TNM tumor-node-metastasis
  7. ARDS Acute respiratory distress syndrome