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Table 1 Demographic data of the study subjects in MPM microarrays

From: CDKN2A copy number and p16 expression in malignant pleural mesothelioma in relation to asbestos exposure

 

Malignant pleural mesothelioma n = 92

Quality controlsb

Asbestos fiber counta ≥ 1.0 × 106 f/g

Asbestos fiber counta 0–0.5 × 106 f/g

Fiber count not available

 

n = 53

n = 22

n = 17

n = 7

Gender, male

50 (94%)

16 (73%)

8 (47%)

2 (29%)

Age, mean ± SD, y

63.7 ± 8.7

68.1 ± 10.2

61.5 ± 8.3

56.9 ± 9.4

Pulmonary fiber counta, median (range), million f/g

8.9 (1.1–1000)

0.2 (0–0.5)

NA

0.8 (0.4–16.0)c

Mesothelioma histologic type

 Epithelioid

43 (81%)

11 (50%)

9 (53%)

–

 Biphasic

4 (8%)

6 (27%)

3 (18%)

–

 Sarcomatoid

6 (11%)

5 (23%)

5 (29%)

–

  1. aPulmonary asbestos fiber counts by scanning electron microscopy (SEM) or transmission electron microscopy (TEM): million fibres per gram dry lung (detection limit ~ < 0.1 million f/g); bMethodologic quality controls had either serous ovarian carcinoma, serous ovarian or peritoneal carcinoma, adenocarcinoma of the lung or pleomorphic liposarcoma; cFiber counts were known for three cases only, thus controls were not used in asbestos-related analysis
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BMC Cancer

ISSN: 1471-2407

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