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Fig. 2 | BMC Cancer

Fig. 2

From: Prediction of response to pemetrexed in non-small-cell lung cancer with immunohistochemical phenotyping based on gene expression profiles

Fig. 2

Boxplots of gene and protein expression levels of selected markers in predicted responders and non-responders to pemetrexed in the training group. Boxplots (Tukey) representing medians and interquartile ranges of relative mRNA expression and IHC staining scores respectively. Whiskers represent minimum and maximum 1.5 interquartile range and dots are outliers. Abbreviations: IHC, immunohistochemical; EZH2, Enhancer of zeste homolog; TOP2A, Topoisomerase II; TPX2, Microtubule Nucleation Factor; CPA3, Carboxypeptidase A3; MCM2, Minichromosome Maintenance Complex Component 2. Abbreviations: IHC, immunohistochemical; EZH2, Enhancer of zeste homolog; TOP2A, Topoisomerase II Alpha; TPX2, Microtubule Nucleation Factor; CPA3, Carboxypeptidase A3; MCM2, Minichromosome Maintenance Complex Component 2

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