Fig. 6From: Differences in colonic crypt morphology of spontaneous and colitis-associated murine models via second harmonic generation imaging to quantify colon cancer development(a, b) Mean and standard deviation of crypt nearest neighbors at 40 μm depth. (c) Standard deviation of crypt circularities at 60 μm depth. (d) Standard deviation of crypt circularity at a range of imaging depths in microns, for AOM late cohort. Cohort n values (stacks): AOM early n = 8, AOM late n = 9, AOM-DSS early n = 5, AOM-DSS late n = 12, Control n = 9. Significance was calculated via two-way ANOVA with Tukey’s post-test. Error bars are standard error. Significance was noted (*) for p values < 0.05 and (**) for p values < 0.01Back to article page