Fig. 5

(a) Mean values of nearest neighbor, (b) the mean values of the standard deviation of crypt nearest neighbor, and (c) the mean values of the standard deviation of circularity. Cohort n values (images): AOM early n = 48, AOM late n = 23, AOM-DSS early n = 45, AOM-DSS late n = 24, Control n = 55. Error bars are standard error; significance was calculated via a nested one-way ANOVA with Tukey’s HSD post-test. Significance was noted (*) for p values < 0.05 and (**) for p values < 0.01