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Table 3 Bivariate logistic regression analyses of children and adolescent characteristics

From: Prevalence and factors associated with major depressive disorder in children and adolescents at the Uganda Cancer Institute

Characteristic Depression
(N = 91)
n (%)
No depression
(N = 261)
n (%)
OR (95% CI) P value
Age
 (7–9 years) 14(15.4) 101(38.7) 1  
  (10-17 years) 77(84.6) 160(61.3) 3.47(1.83–6.56) < 0.001
Region of origin
 Central Uganda 25(27.5) 89(34.1) 1  
 Eastern Uganda 25(27.5) 46(17.6) 1.5(0.49–4.77) 0.45
 Western Uganda 16(17.6) 67(25.7) 0.85(0.41–1.7) 0.65
 Northern Uganda 210(21.9) 47(18) 1.51(0.75–3.0) 0.23
 Foreigners 5(5.5) 12(4.6) 1.45(0.47–4.63) 0.49
Orphanhood status
 Not orphan 63(69.2) 180(69.0) 1  
 Single orphan 23(37.7) 96(36.8) 2.07(1.11–3.76) 0.01
 Double orphan 5(5.4) 14(6.0) 2.44(0.76–8.03) 0.12
HIV status
 Negative 72(79.1) 233(89.3) 1  
 Positive 19(20.9) 28(10.7) 2.19(1.15–4.19) 0.01
Cancer category
 Lymphomas 31(34.1) 121(46.4) 1  
 Leukaemia’s 23(25.3) 71(27.2) 1.26(0.68–2.34) 0.45
 Embryonal tumours 15(16.5) 34(13.0) 1.72(0.82–3.57) 0.13
 Primary bone tumours 3(3.3) 11(4.2) 1.06(0.27–4.06) 0.92
 Others 19(20.9) 24(9.2) 3.09(1.47–6.48) < 0.001
Treatment duration
 0–12 months 72(79.1) 167(64.0) 1  
 12–36 months 15(16.5) 88(33.7) 0.39(0.21–0.73) 0.002
  > 36 months 4(4.4) 6(2.3) 1.54(0.42–5.6) 0.50
Relationship with caregiver
 Parent 46(50.4) 157(60.2) 1  
 Relative 12(13.2) 30(11.5) 1.36(0.64–2.88) 0.43
 Sibling 7(7.7) 19(7.3) 1.25(0.49–3.18) 0.62
 Self (no relative/no caregiver) 23(25.3) 54(20.7) 1.45(0.80–2.62) 0.21
 Other (friend/caretaker) 3(3.3) 1(0.4) 10.23(1.0–104.8) 0.01
Negative coping strategies
 Denial
  Yes 37(40.7) 104(39.8) 1.03(0.63–1.68) 0.89
  No 54(59.3) 157(60.2) 1  
 Self-blame
 Yes 20(22) 36(13.8) 1.76(0.95–3.24) 0.06
 No 71(78) 225(86.2) 1  
 Substance use
  Yes 3(3.3) 14(5.4) 0.60(0.16–2.14) 0.42
  No 88(96.7) 249(94.6) 1  
 Behavioural disengagement
  Yes 51(56) 122(46.7) 1.42(0.89–2.35) 0.12
  No 40(44) 139(53.3) 1  
Positive coping strategies
 Self-distraction
  Yes 40(44) 210(80.5) 0.19(0.10–0.33) < 0.001
  No 51(56) 51(19.5) 1  
 Active coping
  Yes 85(93.4) 244(93.5) 0.98(0.37–2.58) 0.97
  No 6(6.6) 17(6.5) 1  
 Use of emotional support
  Yes 72(79.1) 229(87.7) 0.52(0.28–0.99) 0.04
  No 19(20.9) 32(12.3) 1  
 Use of instrumental support
  Yes 73(80.2) 222(85.1) 0.71(0.38–1.32) 0.28
  No 18(19.8) 39(14.9) 1  
 Acceptance
  Yes 42(46.2) 148(56.7) 0.65(0.40–1.05) 0.08
  No 49(53.8) 113(43.3) 1  
 Positive reframing
  Yes 27(29.7) 176(67.4) 0.51(0.31–0.84) 0.07
  No 44(70.3) 85(32.6) 1  
 Use of religion
  Yes 63(69.2) 201(77) 0.67(0.39–1.14) 0.14
  No 28(30.8) 60(23) 1  
Perception of social support
 Special person in patient’s life
  Yes 63(69.2) 229(87.7) 0.34(0.18–0.61) 0.002
  No 28(30.8) 32(12.3) 1  
 Emotional Support from family
  Yes 65(71.4) 228(87.4) 0.39(0.21–0.71) 0.001
  No 26(28.6) 33(12.6) 1  
 Friends in patient’s life
  Yes 64(70.3) 226(86.6) 0.36(0.20–0.65) 0.004
  No 27(29.7) 35(13.4) 1  
 Family help
  Yes 65(71.4) 227(87) 0.40(0.23–0.73) 0.001
  No 26(28.6) 34(13) 1