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Table 3 Bivariate logistic regression analyses of children and adolescent characteristics

From: Prevalence and factors associated with major depressive disorder in children and adolescents at the Uganda Cancer Institute

Characteristic

Depression

(N = 91)

n (%)

No depression

(N = 261)

n (%)

OR (95% CI)

P value

Age

 (7–9 years)

14(15.4)

101(38.7)

1

 

  (10-17 years)

77(84.6)

160(61.3)

3.47(1.83–6.56)

< 0.001

Region of origin

 Central Uganda

25(27.5)

89(34.1)

1

 

 Eastern Uganda

25(27.5)

46(17.6)

1.5(0.49–4.77)

0.45

 Western Uganda

16(17.6)

67(25.7)

0.85(0.41–1.7)

0.65

 Northern Uganda

210(21.9)

47(18)

1.51(0.75–3.0)

0.23

 Foreigners

5(5.5)

12(4.6)

1.45(0.47–4.63)

0.49

Orphanhood status

 Not orphan

63(69.2)

180(69.0)

1

 

 Single orphan

23(37.7)

96(36.8)

2.07(1.11–3.76)

0.01

 Double orphan

5(5.4)

14(6.0)

2.44(0.76–8.03)

0.12

HIV status

 Negative

72(79.1)

233(89.3)

1

 

 Positive

19(20.9)

28(10.7)

2.19(1.15–4.19)

0.01

Cancer category

 Lymphomas

31(34.1)

121(46.4)

1

 

 Leukaemia’s

23(25.3)

71(27.2)

1.26(0.68–2.34)

0.45

 Embryonal tumours

15(16.5)

34(13.0)

1.72(0.82–3.57)

0.13

 Primary bone tumours

3(3.3)

11(4.2)

1.06(0.27–4.06)

0.92

 Others

19(20.9)

24(9.2)

3.09(1.47–6.48)

< 0.001

Treatment duration

 0–12 months

72(79.1)

167(64.0)

1

 

 12–36 months

15(16.5)

88(33.7)

0.39(0.21–0.73)

0.002

  > 36 months

4(4.4)

6(2.3)

1.54(0.42–5.6)

0.50

Relationship with caregiver

 Parent

46(50.4)

157(60.2)

1

 

 Relative

12(13.2)

30(11.5)

1.36(0.64–2.88)

0.43

 Sibling

7(7.7)

19(7.3)

1.25(0.49–3.18)

0.62

 Self (no relative/no caregiver)

23(25.3)

54(20.7)

1.45(0.80–2.62)

0.21

 Other (friend/caretaker)

3(3.3)

1(0.4)

10.23(1.0–104.8)

0.01

Negative coping strategies

 Denial

  Yes

37(40.7)

104(39.8)

1.03(0.63–1.68)

0.89

  No

54(59.3)

157(60.2)

1

 

 Self-blame

 Yes

20(22)

36(13.8)

1.76(0.95–3.24)

0.06

 No

71(78)

225(86.2)

1

 

 Substance use

  Yes

3(3.3)

14(5.4)

0.60(0.16–2.14)

0.42

  No

88(96.7)

249(94.6)

1

 

 Behavioural disengagement

  Yes

51(56)

122(46.7)

1.42(0.89–2.35)

0.12

  No

40(44)

139(53.3)

1

 

Positive coping strategies

 Self-distraction

  Yes

40(44)

210(80.5)

0.19(0.10–0.33)

< 0.001

  No

51(56)

51(19.5)

1

 

 Active coping

  Yes

85(93.4)

244(93.5)

0.98(0.37–2.58)

0.97

  No

6(6.6)

17(6.5)

1

 

 Use of emotional support

  Yes

72(79.1)

229(87.7)

0.52(0.28–0.99)

0.04

  No

19(20.9)

32(12.3)

1

 

 Use of instrumental support

  Yes

73(80.2)

222(85.1)

0.71(0.38–1.32)

0.28

  No

18(19.8)

39(14.9)

1

 

 Acceptance

  Yes

42(46.2)

148(56.7)

0.65(0.40–1.05)

0.08

  No

49(53.8)

113(43.3)

1

 

 Positive reframing

  Yes

27(29.7)

176(67.4)

0.51(0.31–0.84)

0.07

  No

44(70.3)

85(32.6)

1

 

 Use of religion

  Yes

63(69.2)

201(77)

0.67(0.39–1.14)

0.14

  No

28(30.8)

60(23)

1

 

Perception of social support

 Special person in patient’s life

  Yes

63(69.2)

229(87.7)

0.34(0.18–0.61)

0.002

  No

28(30.8)

32(12.3)

1

 

 Emotional Support from family

  Yes

65(71.4)

228(87.4)

0.39(0.21–0.71)

0.001

  No

26(28.6)

33(12.6)

1

 

 Friends in patient’s life

  Yes

64(70.3)

226(86.6)

0.36(0.20–0.65)

0.004

  No

27(29.7)

35(13.4)

1

 

 Family help

  Yes

65(71.4)

227(87)

0.40(0.23–0.73)

0.001

  No

26(28.6)

34(13)

1