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Table 3 IHC expression of minichromosome maintenance protein 6 and correlation to the patients´ outcome

From: Prognostic relevance of topoisomerase II α and minichromosome maintenance protein 6 expression in colorectal cancer

  N OS [months] DFS [months]
expression   expression  
> 85% ≤85% p > 85% ≤85% p
all 570 n.a. 87.0 0.008 n.a. 51.0 0.001
age (years)
 < 65 270 n.a. 136.0 0.007 n.a. n.a. 0.418
 ≥ 65 280 82.0 51.9 0.246 n.a. n.a. 0.419
tumor site
 right colon 162 104.3 49.8 0.026 n.a. n.a. 0.135
 left colon + rectum 385 n.a. 110.1 0.086 n.a. n.a. 0.658
UICC
 I + II 262 154.6 154.6 0.745 n.a. n.a. 0.965
 III 184 84.0 84.0 0.414 n.a. n.a. 0.373
 IV 101 16.4 16.4 0.199 13.6 21.5 0.423
histological grading
 I 9 n.a. n.a. n.a. n.a. n.a. n.a.
 II 448 n.a. 104.9 0.008 n.a. n.a. 0.149
 III 92 104.3 33.7 0.393 n.a. n.a. 0.839
histology
 adeno carcinoma 466 n.a. 104.9 0.026 n.a. n.a. 0.837
 mucinous + signet-ring carcinoma 75 11.3 41.9 0.103 n.a. 34.7 0.006
resection margin
 R0 509 n.a. 130.5 0.115 n.a. n.a. 0.244
 R1 + R2 29 11,3 15.3 0.308 9,7 n.a. 0.001
  1. All P values in bold, are regarded as statistically significant. Abbreviations: UICC – Union internationale contre le cancer; n.a. – not achieved