Development and validation of a model that includes two ultrasound parameters and the plasma D-dimer level for predicting malignancy in adnexal masses: an observational study

Table 6 The calculated performance indices for different models and SUA for the testing group (n = 100)

Model / Method	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)	AUC
ADNEX	88.0%	94.0%	93.6%	88.7%	0.972
ADNEX	(76.2–94.4)	(83.8–97.9)	(82.8–97.8)	(77.4–94.7)	(0.946–0.999)
LR2	72.0%	98.0%	97.3%	77.8%	0.969
LR2	(58.3–82.5)	(89.5–99.9)	(86.2–99.9)	(66.1–86.3)	(0.936–1.0)
RMI3	82.0%	88.0%	87.2%	83.0%	0.912
RMI3	(69.2–90.2)	(76.2–94.4)	(74.8–94.0)	(70.8–90.8)	(0.854–0.970)
RMI4	84.0%	86.0%	85.7%	84.3%	0.932
RMI4	(71.5–91.7)	(73.8–93.0)	(73.3–92.9)	(72.0–91.8)	(0.882–0.983)
SRrisk	82%	96.0%	95.3%	84.2%	0.976
SRrisk	(69.2–90.2)	(86.5–98.9)	(84.5–98.7)	(72.6–91.5)	(0.953–0.999)
SUA	92.0%	94.0%	93.9%	92.2%	0.930
SUA	(81.2–96.8)	(83.8–97.9)	(83.5–97.9)	(81.5–96.9)	(0.880–0.981)
Our model	96.0%	86.0%	87.3%	95.6%	0.977
Our model	(86.5–98.9)	(73.8–93.0)	(76.0–93.7)	(85.2–98.8)	(0.955–0.999)

95% CI 95% confidence intervals, ADNEX, LR2, RMI3, RMI4, SRrisk abbreviations for different models (details in the text), AUC area under the curve, NPV negative predictive value, PPV positive predictive value, RMI risk of malignancy index (model), SUA subjective ultrasound assessment

ISSN: 1471-2407