Skip to main content

Table 2 Patient characteristics and a comparison between patients with malignant and patients with benign ovarian lesions (n = 290)

From: Development and validation of a model that includes two ultrasound parameters and the plasma D-dimer level for predicting malignancy in adnexal masses: an observational study

Variable

All (n = 290)

Benign (n = 139)

Malignant (n = 151)

Mann-Whitney U test – p value

Age, years, median (Q1, Q3)

53 (41, 63)

45 (35, 55)

58 (49, 66)

p < 0.001

Postmenopausal, n(%)

158 (54.5)

48 (34.5)

110 (72.9)

p < 0.001

Ultrasound variables

 Mulilocular cyst, n(%)

131 (45.2)

46 (33.1)

85 (56.3)

p < 0.001

 Solid areas, n(%)

199 (68.6)

52 (37.4)

147 (97.4)

p < 0.001

 Bilateral lesions, n(%)

64 (22.1)

3 (2.26)

61 (40.4)

p < 0.001

 Ascites, n(%)

57 (19.7)

3 (2.2)

54 (35.8)

p < 0.001

 Metastases in abdominal cavity, n(%)

57 (19.7)

1 (0.7)

56 (37.1)

p < 0.001

 Largerst diameter of tumor, mm, median (Q1, Q3)

67.0 (47.0, 122.8)

60.0 (50.0, 97.5)

84.0 (42.5, 140.0)

p = 0.15

 Color Score

–

–

–

p < 0.001

 Color Score 1, n(%)

178 (61.4)

117 (84.2)

61 (40.4)

 

 Color Score 2, n(%)

84 (29.0)

22 (15.8)

62 (41.1)

 

 Color Score 3, n(%)

25 (8.6)

0 (0.0)

25 (16.6)

 

 Color Score 4, n(%)

3 (1.0)

0 (0.0)

3 (2.0)

 

 RI, PI, PSV not detected, n(%)

212 (73.1)

121 (87.1)

91 (60.3)

p < 0.001

 detected RI, median (range)

0.46 (0–0.73)

0.45 (0–0.73)

0.47 (0.20–0.70)

p = 0.506

 detected PI, median (range)

0.70 (0–2.45)

0.73 (0–1.65)

0.66 (0.28–2.45)

p = 0.280

 detected PSV, median (range)

14.3 (4.69–56.30)

14.40 (4.69–23.37)

14.14 (5.00–56.30)

p = 0.565

Laboratory variables

 CA125, U/ml, median (Q1, Q3)

75.5 (24.0, 438.0)

29.0 (15.0, 65.5)

291.0 (77.5, 897.0)

p < 0.001

 PLT, G/l, median (Q1, Q3)

287.5 (239.0, 365.0)

262.0 (231.0, 302.5)

322.0 (252.0, 424.5)

p < 0.001

 D-dimer, ÎŒg/ml, median (Q1, Q3)

0.779 (0.337, 3.039)

0.354 (0.277, 0.534)

2.837 (1.207, 6.064)

p < 0.001

  1. CA125 cancer antigen 125, PLT platelet count, Q quartile