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Table 2 Patient characteristics and a comparison between patients with malignant and patients with benign ovarian lesions (n = 290)

From: Development and validation of a model that includes two ultrasound parameters and the plasma D-dimer level for predicting malignancy in adnexal masses: an observational study

Variable All (n = 290) Benign (n = 139) Malignant (n = 151) Mann-Whitney U test – p value
Age, years, median (Q1, Q3) 53 (41, 63) 45 (35, 55) 58 (49, 66) p < 0.001
Postmenopausal, n(%) 158 (54.5) 48 (34.5) 110 (72.9) p < 0.001
Ultrasound variables
 Mulilocular cyst, n(%) 131 (45.2) 46 (33.1) 85 (56.3) p < 0.001
 Solid areas, n(%) 199 (68.6) 52 (37.4) 147 (97.4) p < 0.001
 Bilateral lesions, n(%) 64 (22.1) 3 (2.26) 61 (40.4) p < 0.001
 Ascites, n(%) 57 (19.7) 3 (2.2) 54 (35.8) p < 0.001
 Metastases in abdominal cavity, n(%) 57 (19.7) 1 (0.7) 56 (37.1) p < 0.001
 Largerst diameter of tumor, mm, median (Q1, Q3) 67.0 (47.0, 122.8) 60.0 (50.0, 97.5) 84.0 (42.5, 140.0) p = 0.15
 Color Score p < 0.001
 Color Score 1, n(%) 178 (61.4) 117 (84.2) 61 (40.4)  
 Color Score 2, n(%) 84 (29.0) 22 (15.8) 62 (41.1)  
 Color Score 3, n(%) 25 (8.6) 0 (0.0) 25 (16.6)  
 Color Score 4, n(%) 3 (1.0) 0 (0.0) 3 (2.0)  
 RI, PI, PSV not detected, n(%) 212 (73.1) 121 (87.1) 91 (60.3) p < 0.001
 detected RI, median (range) 0.46 (0–0.73) 0.45 (0–0.73) 0.47 (0.20–0.70) p = 0.506
 detected PI, median (range) 0.70 (0–2.45) 0.73 (0–1.65) 0.66 (0.28–2.45) p = 0.280
 detected PSV, median (range) 14.3 (4.69–56.30) 14.40 (4.69–23.37) 14.14 (5.00–56.30) p = 0.565
Laboratory variables
 CA125, U/ml, median (Q1, Q3) 75.5 (24.0, 438.0) 29.0 (15.0, 65.5) 291.0 (77.5, 897.0) p < 0.001
 PLT, G/l, median (Q1, Q3) 287.5 (239.0, 365.0) 262.0 (231.0, 302.5) 322.0 (252.0, 424.5) p < 0.001
 D-dimer, μg/ml, median (Q1, Q3) 0.779 (0.337, 3.039) 0.354 (0.277, 0.534) 2.837 (1.207, 6.064) p < 0.001
  1. CA125 cancer antigen 125, PLT platelet count, Q quartile