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Fig. 1 | BMC Cancer

Fig. 1

From: Genomic profiling in ovarian cancer retreated with platinum based chemotherapy presented homologous recombination deficiency and copy number imbalances of CCNE1 and RB1 genes

Fig. 1

Homologous recombination deficiency scores according to the response to platinum rechallenge. a Telomeric allelic imbalance (tAI); b Loss of heterozygosity score (LOH); c Large scale transition score (LST); d Composite score (CS). Overall response rates according to molecular alterations. e Telomeric allelic imbalance score (tAI) Loss of heterozygosity score (LOH); Large scale transition score (LST) and Composite score (CS); f BRCA mutation; Homologous recombination (HR) gene mutation; CCNE1 copy number gain; CCNE1 copy number gain and RB1 copy number loss

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