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Table 5 Variables that had significant influence on overall survival in a subset of 148 patients with curative radio-chemotherapy or radiotherapy (univariate analysis)

From: Blood serum proteins as biomarkers for prediction of survival, locoregional control and distant metastasis rate in radiotherapy and radio-chemotherapy for non-small cell lung cancer

Variable

Categories (No)

3-year OS

p-value

(HR)

Gender

M

111

25.6%

0.02

F

37

45.0%

(0.58)

Pathology

squamous

90

22.0%

0.005 *

adeno

22

51.0%

(0.42)

NOS

36

39.9%

 

N stage

0–1

40

18.8%

0.02

2–3

107

34.4%

(0.60)

N/A

1

  

Smoking status

never

12

64.2%

< 0.04

ever

136

28.2%

(2.76)

VEGF (n = 125)

< 362 pg/ml

62

38.7%

0.006

≥362 pg/ml

63

22.7%

(1.89)

EPO (n = 96)

< 16.1 mlU/ml

51

40.3%

0.008

≥16.1 mlU/ml

45

15.9%

(2.02)

  1. *comparison between squamous-cell cell cancer and adenocarcinoma