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Table 3 Top genes with > 10 mutations in PDAC tumors from TCGA (provisional, accessed January 17, 2014)

From: High methylation levels of PCDH10 predict poor prognosis in patients with pancreatic ductal adenocarcinoma

Gene Cytoband Gene size (Nucleotides) n. Mutations
TP53 17p13.1 3924 37
PCDHGC5 5q31 4641 36
KRAS 12p12.1 7302 33
ZFHX3 16q22.3 17,503 26
PCDHAC2 5q31 5970 26
TCF20 22q13.3|22q13.3 7548 24
CHD3 17p13.1 9758 16
PCDH15 10q21.1 14,967 16
GIGYF1 7q22 6709 15
PCDH10 4q28.3 5516 15
ANK3 10q21 22,521 14
MED15 22q11.2 10,374 14
GZF1 20p11.21 5495 14
KIAA0907 1q22 5635 14
TTBK2 15q15.2 11,642 13
SUPT6H 17q11.2 10,615 13
GRM1 6q24 7272 13
CDKN2A 9p21 4400 13
RANGAP1 22q13 5463 13
CHD4 12p13 7474 12
ZFC3H1 12q21.1 9670 12
TAOK2 16p11.2 9058 12
SIPA1L1 14q24.2 12,412 12
HOXA1 7p15.3 2539 12
PASD1 Xq28 4429 12
NOS1AP 1q23.3 8449 12
ZMIZ1 10q22.3 10,735 12
TMCC1 3q22.1 7912 12
MAMLD1 Xq28 5958 12
SMARCC2 12q13.2 8555 11
CDH10 5p14.2 3660 11
FTSJ3 17q23.3 5213 11
MUC4 3q29 21,325 11
MED12L 3q25.1 12,619 11
TCHH 1q21.3 6900 11
MAGEC1 Xq26 4270 11
NAV2 11p15.1 14,577 11
RSPH6A 19q13.3 2547 11
FUZ 19q13.33 2951 11
SF3A1 22q12.2 6327 11
CDC27 17q21.32 6823 11
FOXN3 14q31.3 11,033 11
CXXC1 18q12 4319 11