Table 3 Top genes with > 10 mutations in PDAC tumors from TCGA (provisional, accessed January 17, 2014)

TP53

17p13.1

3924

37

PCDHGC5

5q31

4641

36

KRAS

12p12.1

7302

33

ZFHX3

16q22.3

17,503

26

PCDHAC2

5q31

5970

26

TCF20

22q13.3|22q13.3

7548

24

CHD3

17p13.1

9758

16

PCDH15

10q21.1

14,967

16

GIGYF1

7q22

6709

15

PCDH10

4q28.3

5516

15

ANK3

10q21

22,521

14

MED15

22q11.2

10,374

14

GZF1

20p11.21

5495

14

KIAA0907

1q22

5635

14

TTBK2

15q15.2

11,642

13

SUPT6H

17q11.2

10,615

13

GRM1

6q24

7272

13

CDKN2A

9p21

4400

13

RANGAP1

22q13

5463

13

CHD4

12p13

7474

12

ZFC3H1

12q21.1

9670

12

TAOK2

16p11.2

9058

12

SIPA1L1

14q24.2

12,412

12

HOXA1

7p15.3

2539

12

PASD1

Xq28

4429

12

NOS1AP

1q23.3

8449

12

ZMIZ1

10q22.3

10,735

12

TMCC1

3q22.1

7912

12

MAMLD1

Xq28

5958

12

SMARCC2

12q13.2

8555

11

CDH10

5p14.2

3660

11

FTSJ3

17q23.3

5213

11

MUC4

3q29

21,325

11

MED12L

3q25.1

12,619

11

TCHH

1q21.3

6900

11

MAGEC1

Xq26

4270

11

NAV2

11p15.1

14,577

11

RSPH6A

19q13.3

2547

11

FUZ

19q13.33

2951

11

SF3A1

22q12.2

6327

11

CDC27

17q21.32

6823

11

FOXN3

14q31.3

11,033

11

CXXC1

18q12

4319

11