Table 2 Results from the EORTC QLQ-C30 version 3.0 and utility assessment of head and neck cancer survivors. A comparison of head and neck cancer patients with a report from the Swedish population [3]
From: Health-related quality of life and utility in head and neck cancer survivors
Oral cancer (n = 51) | Nasopharyngeal cancer (n = 24) | Oropharyngeal cancer (n = 15) | Hypopharyngeal cancer (n = 10) | Laryngeal cancer (n = 10) | Thyroid cancer (n = 17) | Total (n = 127) | Published reference norm values (n = 562) | p1 | Published Head and neck cancer survivors | p2 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
(n = 133) | |||||||||||
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||
Functional scales | |||||||||||
Physical functioning | 89.80 (20.28) | 93.05 (8.67) | 90.67 (12.03) | 94(8.58) | 75.33 (27.41) | 96.86 (5.33) | 90.66 (16.78) | 88.9 (18.1) | 0.28 | 85.6 (21.2) | 0.03 |
Role functioning | 95.42 (20.02) | 95.83 (14.95) | 95.56 (17.21) | 100 | 88.33 (22.29) | 100 | 95.93 (16.63) | 86.5 (24.8) | < 0.01 | 83.3 (30.1) | < 0.01 |
Emotional functioning | 88.73 (15.08) | 86.81 (19.18) | 92.78 (14.04) | 94.17 (11.15) | 93.33 (10.97) | 81.86 (18.22) | 88.71 (15.87) | 84.6 (20.1) | 0.01 | 85.0 (18.7) | 0.09 |
Cognitive functioning | 85.29 (17.53) | 81.94 (13.83) | 84.44 (18.33) | 95 (11.25) | 83.33 (15.71) | 78.43 (18.41) | 84.25 (16.7) | 89.5 (20.6) | < 0.01 | 86.0 (22.2) | 0.4 |
Social functioning | 92.16 (19.25) | 95.83 (8.86) | 97.78 (8.61) | 96.67 (7.03) | 93.33 (19.56) | 92.16 (10.40) | 93.96 (14.80) | 86.9 (18.1) | < 0.01 | 87.0 (16.5) | < 0.01 |
Symptom scales/items | |||||||||||
Fatigue | 16.56 (24.68) | 14.81 (19.29) | 14.07 (27.69) | 10 (15.23) | 18.89 (20.98) | 17.65 (20.05) | 15.75 (22.33) | 19.7 (21.4) | 0.07 | 22.8 (22.9) | 0.01 |
Nausea and vomiting | 2.29 (7.47) | 2.78 (8.03) | 0 | 5 (11.25) | 3.33 (10.54) | 1.96 (8.09) | 2.36 (7.78) | 3.3 (11.0) | 0.28 | 3.1 (9.0) | 0.5 |
Pain | 17.97 (25.9) | 10.42 (13.74) | 10 (16.43) | 16.67 (22.22) | 26.67 (33.52) | 8.82 (8.58) | 14.96 (21.91) | 17.7 (24.6) | 0.22 | 14.9 (20.7) | 0.97 |
Dyspnea | 6.54 (20.02) | 2.78 (9.41) | 8.89 (19.79) | 6.67 (14.06) | 13.33 (23.31) | 1.96 (8.09) | 6.04 (17.02) | 16.5 (24.1) | < 0.01 | 17.8 (23.9) | < 0.01 |
Insomnia | 24.2 (36.6) | 9.7 (18.3) | 8.9 (26.6) | 23.3 (31.6) | 20 (28.1) | 25.5 (27.7) | 19.4 (30.7) | 16.5 (24.9) | 0.32 | 18.8 (26.4) | 0.87 |
Appetite loss | 8.50 (21.95) | 11.11 (25.38) | 15.56 (30.52) | 16.67 (17.57) | 16.67 (28.33) | 7.84 (14.57) | 11.02 (23.02) | 3.4 (12.7) | < 0.01 | 11.7 (25.1) | 0.81 |
Constipation | 11.76 (19.80) | 9.72 (20.80) | 11.11 (27.22) | 6.67 (14.05) | 6.67 (14.05) | 17.65 (20.81) | 11.28 (20.24) | 5.1 (15.9) | < 0.01 | 3.8 (11.4) | < 0.01 |
Diarrhea | 4.58 (16.35) | 4.17 (11.26) | 0 | 3.33 (10.54) | 3.33 (10.54) | 17.65 (29.15) | 5.51 (16.67) | 5.0 (16.0) | 0.75 | 10.8 (21.9) | 0.03 |
Financial difficulties | 7.19 (16.75) | 5.56 (16.05) | 11.11 (27.22) | 10 (22.50) | 16.67 (23.57) | 5.88 (13.10) | 8.14 (18.65) | 6.6 (19.7) | 0.41 | 11.6 (25.2) | 0.2 |
Global health status/QOL | |||||||||||
Global health status/QOL | 74.67 (19.86) | 65.97 (19.80) | 70 (28.49) | 71.67 (19.72) | 69.17 (30.44) | 67.65 (22.42) | 70.87 (22.09) | 76.5 (22.0) | < 0.01 | 73.2 (21.3) | 0.4 |
Utility (N = 102) | 0.71 (0.17) | 0.73 (0.20) | 0.76 (0.14) | 0.72 (0.24) | 0.70 (0.20) | 0.70 (0.21) | 0.7 (0.2) | NA | NA | NA | NA |