Fig. 3From: Ιmpact of sunitinib-induced hypothyroidism on survival of patients with metastatic renal cancerEarly increase in TSH predicted longer PFS. Patients with a TSH increase > 2 x baseline value on day-15 exhibited a longer PFS than those with a TSH increase less than twice their baseline value (11.92 vs 8.63 months, HR 1.76, 95% CI: 1.033–3.288, p = 0.0476) (Log-Rank test)Back to article page