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Table 3 Univariate and multivariate analyses of PFS in patients

From: Irreversible electroporation versus radiotherapy after induction chemotherapy on survival in patients with locally advanced pancreatic cancer: a propensity score analysis

Characteristic Before PSM After PSM
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
HR 95%CI P HR 95%CI P HR 95%CI P HR 95% CI P
Age (years) ≤60/> 60 1.178 0.674–2.058 0.566    NI 0.956 0.547–1.671 0.874    NI
Gender Female / Male 1.587 0.905–2.783 0.107    NI 2.284 1.269–4.112 0.006 1.798 0.966–3.330 0.064
Tumor size (cm) ≤2/2~4/>4 0.787 0.490–1.265 0.324    NI 0.970 0.596–1.579 0.903    NI
Tumor grade Well / Moderate / Poor 1.135 0.735–1.753 0.568    NI 1.333 0.855–2.079 0.205    NI
LN metastasis Absent / Present 0.900 0.501–1.614 0.723    NI 1.078 0.600–1.938 0.801    NI
Tumor site Head / Body / Tail 0.935 0.621–1.407 0.748    NI 0.995 0.650–1.525 0.983    NI
WBC (*109) ≤10/>10 1.149 0.486–2.718 0.751    NI 1.019 0.431–2.411 0.965    NI
HGB (g/L) ≤120/>120 0.685 0.308–1.527 0.355    NI 0.477 0.211–1.076 0.075    NI
PLT (*109) ≤300/>300 0.613 0.261–1.438 0.261    NI 0.676 0.287–1.592 0.370    NI
ALT (U/L) ≤40/>40 0.729 0.373–1.426 0.356    NI 0.737 0.375–1.447 0.375    NI
AST (U/L) ≤40/>40 0.662 0.309–1.417 0.288    NI 0.691 0.320–1.490 0.345    NI
ALP (U/L) ≤100/>100 0.823 0.459–1.476 0.514    NI 0.790 0.439–1.423 0.433    NI
GGT (U/L) ≤45/>45 0.693 0.390–1.230 0.210    NI 0.741 0.414–1.327 0.313    NI
ALB (g/L) ≤40/>40 0.602 0.253–1.429 0.250    NI 0.666 0.281–1.582 0.357    NI
TBIL (umol/L) ≤20.5/>20.5 0.691 0.336–1.423 0.316    NI 0.721 0.350–1.487 0.376    NI
IBIL (umol/L) ≤15/>15 0.884 0.317–2.461 0.813    NI 0.769 0.276–2.144 0.616    NI
CRP (ng/L) ≤3/>3 1.840 1.030–3.286 0.040 1.586 0.877–2.866 0.127 1.763 0.970–3.202 0.063    NI
CEA (ng/mL) ≤5/>5 1.466 0.835–2.572 0.183    NI 1.464 0.829–2.586 0.189    NI
CA19–9 (U/ml) ≤35/>35 2.078 1.009–4.279 0.047 1.908 0.917–3.968 0.084 2.530 1.179–5.429 0.017 2.032 0.904–4.569 0.086
Chemotherapy With IRE/ With radiotherapy 0.557 0.310–1.000 0.050 0.582 0.322–0.950 0.048 0.435 0.242–0.783 0.005 0.438 0.243–0.790 0.006
Cheotherapy type FOLFIRINOX/Gem 0.965 0.733–1.271 0.803    NI 1.014 0.768–1.340 0.921    NI
  1. Abbreviations as in Table 1