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2 Correlations between liver cirrhosis and clinicopathological features of HCC patients

From: Paracrine effects of CCN3 from non-cancerous hepatic cells increase signaling and progression of hepatocellular carcinoma

Variable

Patients with Cirrhosis (N = 374)

yes

no

p

Age, y

  ≥ 50

171

16

0.101

  < 50

161

26

 

HBsAg

 Positive

318

29

<0.001

 Negative

14

13

 

Serum, AFP (μg/L)

  ≥ 20

216

20

0.026

  < 20

116

22

 

Tumor dimension

  ≥ 5 cm

62

19

<0.001

  < 5 cm

270

23

 

Vascular invasion

 Yes

100

14

0.679

 No

232

28

 

Tumor differentiation

 I-II

253

27

0.096

 III-IV

79

15

 

Sex

 Male

271

35

0.823

 Female

60

7

 

Serum, ALT (IU/L)

  ≥ 60

34

6

0.389

  < 60

298

36

 

No. of tumors

 Multiple

19

0

0.242*

 Single

313

42

 

Tumor encapsulation

 Complete

196

20

0.152

 None

136

22

 

Tumor recurrence

 Yes

165

16

0.162

 No

167

26

 
  1. AFP, alpha-fetoprotein; HBsAg, hepatitis B surface antigen; HCV, hepatitis C virus
  2. *Fisher’s exact test
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BMC Cancer

ISSN: 1471-2407

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