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Table 3 Subgroup analysis for sex difference of gastric cancer (current smoker versus never smoker)

From: Smoking status and subsequent gastric cancer risk in men compared with women: a meta-analysis of prospective observational studies

Group

RRR and 95% CI

P value

Heterogeneity (%)

P value for heterogeneity

P value for interaction test

Publication year

 2000 or after

1.27 (0.93–1.74)

0.130

60.6

0.027

0.921

 Before 2000

1.32 (0.89–1.96)

0.172

38.2

0.183

Country

 Asia

1.50 (1.17–1.91)

0.001

40.2

0.171

0.306

 Europe or US

1.12 (0.77–1.64)

0.548

58.2

0.035

Follow-up duration (years)

 10 or greater

1.33 (1.02–1.74)

0.037

44.7

0.143

0.573

  < 10

1.46 (1.11–1.91)

0.006

22.4

0.272

Outcomes

 GC incidence

0.92 (0.66–1.29)

0.628

16.5

0.309

0.023

 GC mortality

1.53 (1.24–1.89)

< 0.001

39.3

0.143

Adjusted BMI or not

 Yes

1.07 (0.53–2.15)

0.848

68.0

0.025

0.527

 No

1.47 (1.24–1.74)

< 0.001

20.2

0.286

Adjusted alcohol consumption

 Yes

0.99 (0.61–1.61)

0.971

49.6

0.114

0.331

 No

1.53 (1.20–1.94)

0.001

50.2

0.090

NOS score

 7 or 8

1.42 (1.11–1.81)

0.005

43.4

0.101

0.169

  < 7

0.91 (0.41–2.02)

0.814

62.7

0.068