Table 3 Subgroup analysis for sex difference of gastric cancer (current smoker versus never smoker)
Group | RRR and 95% CI | P value | Heterogeneity (%) | P value for heterogeneity | P value for interaction test |
|---|---|---|---|---|---|
Publication year | |||||
2000 or after | 1.27 (0.93–1.74) | 0.130 | 60.6 | 0.027 | 0.921 |
Before 2000 | 1.32 (0.89–1.96) | 0.172 | 38.2 | 0.183 | |
Country | |||||
Asia | 1.50 (1.17–1.91) | 0.001 | 40.2 | 0.171 | 0.306 |
Europe or US | 1.12 (0.77–1.64) | 0.548 | 58.2 | 0.035 | |
Follow-up duration (years) | |||||
10 or greater | 1.33 (1.02–1.74) | 0.037 | 44.7 | 0.143 | 0.573 |
< 10 | 1.46 (1.11–1.91) | 0.006 | 22.4 | 0.272 | |
Outcomes | |||||
GC incidence | 0.92 (0.66–1.29) | 0.628 | 16.5 | 0.309 | 0.023 |
GC mortality | 1.53 (1.24–1.89) | < 0.001 | 39.3 | 0.143 | |
Adjusted BMI or not | |||||
Yes | 1.07 (0.53–2.15) | 0.848 | 68.0 | 0.025 | 0.527 |
No | 1.47 (1.24–1.74) | < 0.001 | 20.2 | 0.286 | |
Adjusted alcohol consumption | |||||
Yes | 0.99 (0.61–1.61) | 0.971 | 49.6 | 0.114 | 0.331 |
No | 1.53 (1.20–1.94) | 0.001 | 50.2 | 0.090 | |
NOS score | |||||
7 or 8 | 1.42 (1.11–1.81) | 0.005 | 43.4 | 0.101 | 0.169 |
< 7 | 0.91 (0.41–2.02) | 0.814 | 62.7 | 0.068 | |