Fig. 3

Upregulation of hsa_circ_0005379 increases apoptosis rate of OSCC cells. Hoechst staining was performed on SCC25 and CAL27 cells transduced with mock control or lentivirus harboring hsa_circ_0005379. The proportion of apoptotic cells was quantified in SCC25 and CAL27 cells. Data are presented as means ± SEM of three independent experiments. Student’s t-test, ***P < 0.001. Scale bar, 20 μm