Table 2 Uni- and multivariate Cox regression analysis of disease recurrence in several PCa datasets

MSKCC

TMCC11

4.10 (2.08, 8.1)

< 0.001

2.27 (1.05,4.91)

0.038

2.35 (1.14,4.87)

0.021

Biop. Gleason

4.26 (1.93, 9.42)

< 0.001

0.96 (0.36,2.59)

0.943

PSA

2.98 (1.53, 5.83)

0.001

1.66 (0.79,3.49)

0.372

Path Stage

4.62 (2.30,9.27)

< 0.001

4.15 (1.56,11.04)

0.459

2.99 (1.42,6.29)

0.004

Surg. margins

2.07 (1.06, 4.06)

0.034

0.90 (0.42,1.95)

0.776

ECE

2.10 (0.92,4.80)

0.79

0.42 (0.12,1.29)

0.415

Surg. Gleason

10.56 (4.87,22.86)

< 0.001

7.92 (3.16,19.87)

< 0.001

6.78 (2.92,15.73)

< 0.001

CAM

TMCC11

4.76 (1.80, 12.59)

0.002

4.28 (1.53, 11.99)

0.006

3.53 (1.31,9.51)

0.013

Biop. Gleason

3.25 (1.32, 8.02)

0.011

1.10 (0.25,4.93)

0.897

PSA

1.50 (0.57, 3.95)

0.412

2.82 (1.00,7.98)

0.050

Surg. Gleason

4.68 (1.88,11.63)

< 0.001

5.12 (1.07, 24.55)

0.041

4.31 (1.70,10.91)

0.002

Surg. margins

1.64 (0.62, 4.35)

0.324

2.08 (0.76,5.71)

0.156

ECE

1.82 (0.60,5.48)

0.288

0.85 (0.28,2.64)

0.780

STO

TMCC11

3.00 (1.65,5.44)

< 0.001

2.69 (1.46,6.11)

0.003

2.89 (1.56,5.36)

< 0.001

Preop. Gleason

2.67 (1.44,4.96)

0.002

1.40 (0.66, 2.99)

0.381

2.12 (1.12,4.02)

0.021

PSA

1.61 (0.89,2.92)

0.116

1.05 (0.56,1.98)

0.879

Surg. Gleason

3.62 (2.00,6.58)

< 0.001

1.77 (0.84,3.74)

0.136

Surg. margins

1.99 (1.10,3.59)

0.023

1.84 (0.96,3.54)

0.068

ECE

4.21 (2.19,8.09)

<.001

2.98 (1.46,6.11)

0.003

3.69 (1.89,7.20)

< 0.001

TCGA

TMCC11

2.94 (1.94, 4.46)

< 0.0001

1.96 (1.26,3.05)

0.003

1.96 (1.26,3.05)

0.003

Gleason

4.08 (2.27, 7.34)

< 0.0001

2.29 (1.20, 4.38)

0.012

2.29 (1.20, 4.38)

0.012

Path Stage

3.68 (2.07, 6.51)

< 0.0001

2.25 (1.22, 4.15)

0.010

2.25 (1.22, 4.15)

0.010