Table 4 Predictors (with hazard ratios (HR)) of Overall Survival (OS) and 2-year survival by multivariable Cox regression analysis
From: The determinants and impact of diagnostic delay in lymphoma in a TB and HIV endemic setting
OS HR (95% CI) | P-value | 2 yr-survival HR (95% CI) | P-value | |
|---|---|---|---|---|
Late-stage (vs early-stage) | 2.0 (1.1–3.8) | 0.03 | 2.0 (1.2–3.4) | < 0.01 |
NHL (vs HL) | 2.5 (1.1–5.0) | 0.05 | 3.1 (1.5–6.3) | 0.05 |
Emergency chemotherapy (vs non-emergency) | 1.2 (0.6–2.3) | 0.70 | 1.7 (0.9–2.9) | 0.12 |
HIV positive (vs negative) | 4.2 (1.9–9.4) | < 0.01 | 5.0 (2.0–12.4) | 0.01 |
Performance status (vs ECOG = 0) | ||||
ECOG 1 | 1.8 (0.5–6.3) | 0.35 | 1.3 (0.5–3.1) | 0.73 |
ECOG 2 | 3.7 (1.0–14.6) | 0.06 | 2.5 (0.9–7.1) | 0.09 |
ECOG 3 | 7.6 (2.1–27.4) | < 0.01 | 6.8 (2.6–17.8) | < 0.01 |
ECOG 4 | 4.5 (1.1–17.6) | 0.03 | 6.2 (2.0–18.7) | < 0.01 |
Diagnostic delay | 0.6 (0.3–1.0) | 0.06 | 0.8 (0.5–1.3) | 0.34 |
Age ≥ 50 (vs < 50) | 4.1 (1.9–8.9) | < 0.01 | 1.7 (1.0–2.6) | 0.03 |