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Table 4 Predictors (with hazard ratios (HR)) of Overall Survival (OS) and 2-year survival by multivariable Cox regression analysis

From: The determinants and impact of diagnostic delay in lymphoma in a TB and HIV endemic setting

  OS HR (95% CI) P-value 2 yr-survival HR (95% CI) P-value
Late-stage (vs early-stage) 2.0 (1.1–3.8) 0.03 2.0 (1.2–3.4) < 0.01
NHL (vs HL) 2.5 (1.1–5.0) 0.05 3.1 (1.5–6.3) 0.05
Emergency chemotherapy (vs non-emergency) 1.2 (0.6–2.3) 0.70 1.7 (0.9–2.9) 0.12
HIV positive (vs negative) 4.2 (1.9–9.4) < 0.01 5.0 (2.0–12.4) 0.01
Performance status (vs ECOG = 0)
 ECOG 1 1.8 (0.5–6.3) 0.35 1.3 (0.5–3.1) 0.73
 ECOG 2 3.7 (1.0–14.6) 0.06 2.5 (0.9–7.1) 0.09
 ECOG 3 7.6 (2.1–27.4) < 0.01 6.8 (2.6–17.8) < 0.01
 ECOG 4 4.5 (1.1–17.6) 0.03 6.2 (2.0–18.7) < 0.01
Diagnostic delay 0.6 (0.3–1.0) 0.06 0.8 (0.5–1.3) 0.34
Age ≥ 50 (vs < 50) 4.1 (1.9–8.9) < 0.01 1.7 (1.0–2.6) 0.03
  1. All the variables in the model are given above
  2. HL Hodgkin lymphoma, NHL Non-Hodgkin lymphoma, ECOG Eastern European Oncology Group