Fig. 2
From: Case report: reinitiating pembrolizumab treatment after small bowel perforation
Diagnosis of PD-L1 positive, metastatic NSCLC and pre-treatment PET/CT imaging. a. Hematoxylin and eosin (H&E) stained neck mass biopsy showing adenocarcinoma cells consistent with primary lung disease. Scale bar = 20 mm. b. Thyroid transcription factor 1 (TTF-1) positive (dark brown staining) tumor cells. Bar = 20 mm. c. Immunohistochemical staining of the patient’s biopsy sample for PD-L1 (Dako 22C3). In the representative image, greater than 80% of tumor cells were PD-L1 positive (brown staining). Scale bar = 20 mm. d. Transverse computed tomography (CT) images with matching positron emission tomography (PET) images below. Detected lesions: a = anterior left upper lung lobe, b = right paratrachel region, c = left lung hilum, d = single splenic lesion