Fig. 6
From: Mitochondrial autoimmunity and MNRR1 in breast carcinogenesis
MNRR1 and cellular growth. a S473 pAKT levels in MNRR1-knockdown (R1-KD) and MNRR1-OE (R1-OE) cells compared to WT controls. Total AKT levels do not change. GAPDH is used as a loading control. b Total Rictor protein levels in WT cells expressing either an empty vector (EV), Flag-tagged WT-MNRR1 (WT), or flag tagged transcriptionally active MNRR1 (TA). Tubulin is used as a loading control. Flag levels indicate transfection efficiency between WT and TA MNRR1. c PGC-1α and Rictor protein levels in MCF7 cells with a knockout of MNRR1. GAPDH is used as a loading control. d Cell growth between MCF10A cells transfected with either an empty vector (EV) or MNRR1 (R1) expression plasmid. The Cell Titre96 assay was measured spectrophotometrically. p = 0.03