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Fig. 1 | BMC Cancer

Fig. 1

From: Nonsynonymous, synonymous and nonsense mutations in human cancer-related genes undergo stronger purifying selections than expectation

Fig. 1

The landscape of human SNPs. a A schematic diagram showing the filtering of SNPs according to the orthologous sites in rhesus monkey and mouse genomes. The phylogenetic tree is unscaled. b A schematic diagram displaying the definition of uni-mutation SNPs. ref., reference. Mut., mutation. c the fractions of different types of mutations. d The annotations and proportions of genomic SNPs (left) and exonic SNPs (right) after the above filtering steps. The clip arts of human/monkey/mouse were drawn by ourselves

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