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Table 1 Detailed Mouse Data from E545K, H1047R or SgPten Combined with c-Met Injected Mice

From: Functional role of SGK3 in PI3K/Pten driven liver tumor development

Injection Sgk3 genotype Number Gender Weeks post injection Body weight (g) Liver weight (g) Histology
E545K/c-Met +/+ 8 F 6.6 23.7 5.8 HCC
F 8 24.2 4.7 HCC
F 8 25.3 5.6 HCC
F 8.3 27.4 5.5 HCC
M 9 32.5 7.4 HCC
F 9.0 26.3 5.0 HCC
M 10.1 31.0 7.1 HCC
M 11.7 31.2 6.3 HCC
−/− 8 F 9.9 26.9 5.3 HCC
F 10.0 26.5 5.2 HCC
M 10.1 35.4 7.4 HCC
F 11.7 26.4 5.4 HCC
M 12 29.3 6.8 HCC
M 13.1 29.9 7.7 HCC
M 13.3 32.8 7.0 HCC
M 18.7 31.2 5.9 HCC
H1047R/c-Met +/+ 5 F 5.6 26.9 5.0 HCC
F 5.9 21.3 5.9 HCC
M 7.1 29.3 6.4 HCC
M 7.6 31.3 5.9 HCC
M 10.6 27.8 5.0 HCC
−/− 5 F 5.6 28.0 6.4 HCC
F 7.6 23.0 6.1 HCC
M 10.1 31.0 6.0 HCC
M 10.4 30.0 6.3 HCC
M 10.6 28.2 6.1 HCC
sgPten/c-Met +/+ 6 F 8 23.1 5.3 HCC
F 9.4 27.3 5.8 HCC
M 10.4 29.2 6.3 HCC
M 10.4 27.9 4.3 HCC
M 12.7 31.8 6.8 HCC
M 12.7 29.6 6.1 HCC
sgPten/c-Met −/− 6 F 9.4 28.2 6.9 HCC
M 9.6 27.5 7.3 HCC
F 10.4 27.2 7.5 HCC
F 12.7 26.8 5.1 HCC
F 15 27.8 7.0 HCC
M 15.6 29.2 8.1 HCC