Fig. 5
From: Functional role of SGK3 in PI3K/Pten driven liver tumor development
Molecular characterization of hepatocellular carcinoma developed in Sgk3+/+ and Sgk3−/− mice injected with E545K, H1047R, or sgPten and c-Met constructs. Levels of SGK3, c-Met, Pten (a) activation of AKT/mTOR, (b) Ras/MAPK pathways, and β-Catenin (c) were assessed by Western blot analysis. Representative images are shown. GAPDH and β-actin were used as loading control. For detail description, please refer to the main text