Differential proteomic comparison of breast cancer secretome using a quantitative paired analysis workflow

BMC Cancer

Table 1 Reproductive and tumor characteristics of the ten unilateral breast cancer cases and three individuals without breast disease analyzed

Subject	Age (years)	Birth control use / hormonal replacement^a	Parity / breastfeeding^b	Familial breast cancer	Bloom-Richardson Grading^c	Cancer staging^d	Immunohistochemistry status
Subject	Age (years)	Birth control use / hormonal replacement^a	Parity / breastfeeding^b	Familial breast cancer	Bloom-Richardson Grading^c	Cancer staging^d	Estrogen receptor	Progesterone receptor	Human Epidermal Growth Factor Receptor 2
Patient 1	64	yes / no	1 / yes	no	I	I	Positive	Negative	Negative
Patient 2	73	no / no	6 / yes	no	II	I	Positive	Positive	Negative
Patient 3	53	yes / no	3 / yes	no	II	I	Positive	Positive	Negative
Patient 4	66	yes / no	7 / yes	no	III	IIB	Negative	Negative	Negative
Patient 5	85	no / no	3 / yes	no	II	I	Positive	Positive	Negative
Patient 6	51	no / no	2 / yes	no	II	IIIA	Negative	Negative	Negative
Patient 7	54	no / no	1 / no	no	III	IIB	Negative	Negative	Negative
Patient 8	60	yes / no	3 / yes	no	III	IIB	Negative	Negative	Positive
Patient 9	51	yes / no	3 / yes	no	II	IIIB	Negative	Negative	Positive
Patient 10	72	yes / yes	2 / yes	NDA^e	II	IIB	Positive	Positive	Negative
Individual 1	59	yes / no	4 / yes	yes	–	–	–	–	–
Individual 2	53	yes / no	3 / yes	no	–	–	–	–	–
Individual 3	61	yes / no	1 / yes	no	–	–	–	–	–

^aBirth control use/hormonal replacement is defined by whether each woman used or not oral contraceptives/ hormone replacement pills
^bBreastfeeding is defined by whether or not the woman feed the baby with milk from the breast for at least 1 month
^cBloom-Richardson grading at Bloom and Richardson (1957)
^dCancer staging classification according to the Brazilian National Institute of Cancer (2004)
^eNDA refers to No Data Available

ISSN: 1471-2407