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Table 1 Domains and measures accessed by CGA before and after treatment

From: A multicenter phase III study comparing Simultaneous Integrated Boost (SIB) radiotherapy concurrent and consolidated with S-1 versus SIB alone in elderly patients with esophageal and esophagogastric cancer – the 3JECROG P-01 study protocol

Domain with measure No. of items Range of score
Quality of life and specific module for EC
 EORTC QLQ-C30 (Version 3.0) [34] 30 30–126
 QLQ-OES-18 [35] 18 18–72
Functional status
 ECOG performance status [36]   0–5
 Karnofsky performance status [37]   0–100
 Activities of daily life (Barthel index) [38] 10 0–100
 Instrumental activities of daily life (Lawton’s) [39] 8 0–5/8
Comorbidity
 Charlson comorbidity index [40] 19 0–37
Cognitive status
 Mini Mental State Examination [41] 11 0–30
Psychological status
 Geriatric depression scale-5 items [42] 5 0–5
Nutritional status
 Body mass index [43]   
 Mini-nutritional assessment [44] 18 0–100
Social support
 Medical Outcomes Study - social support survey [45] 20 20–100
  1. CGA comprehensive geriatric assessment, EC esophageal cancer, ECOG Eastern Cooperative Oncology Group, EORTC The European Organization for Research and Treatment of Cancer, MOS Medical outcomes study